The Genomic Atlas of Breast Cancer — the non-coding theme
LncRNAs
LncRNA methylation interaction
Differential methylated lncRNAs
SNPs
CircRNAs
Mutations
MiRNA-SNP
Enhancers
Super Enhancer
MircoRNAsGABC, The Genomic Atlas of Breast Cancer, is a manually curated database that records multi-omics data associated with breast cancer, including genome (SNP, somatic mutation), transcriptome (lncRNA, miRNA and circRNA) and epigenomics (DNA methylation, enhancer and super-enhancer). The current version of GABC comprise 10,142 entries, it can be retrieved through Browser and Search page. Users can also browse the genomic position of these risk elements through Jbrowse.
1. Dysregulated lncRNAs in breast cancer;
2. LncRNA and DNA methylation regulatory relationships;
3. Predicted differentially methylated lncRNAs;
4. Risk SNPs in breast cancer;
5. Significant mutations in lncRNA;
6. miRNAs and SNPs in miRNAs;
7. Breast cancer associated enhancers;
8. Breast cancer associated super-enhancers;
9. Breast cancer associated circRNAs;
The circos plot display multi-omics data distribution in GABC database.
1. The inner circos indicate the genomic locations of super-enhancers related with breast cancer, the height of each bar represent the score of each super-enhancer.
2. In the outer circos, SNPs, methylation, miRNAs, and enhancers were marked with different colors and shapes.
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