Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p23.3

lncRNA

GTF3C2-AS1 ( ENSG00000234945)

miRNA

hsa-miR-874-3p (MIMAT0004911)

mRNA

E2F3 (ENSG00000112242)

Disease

OV

FDR

2.06E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 AGCCA     C     U     C 5 hsa-miR-874-3p
               GGGAG CCG G CCCGU    
               CCCUC GGC C GGGCA    
target 5     C     U   A U     C 3 GTF3C2-AS1
Start: 300  End: 320
Energy: -31.7 kcal/mol
Align Score: 0.005245
miRNA  3 AG  AG   G      G       U   5 hsa-miR-874-3p
            CC  GGA   CCCG   UCCCG C    
            GG  CCU   GGGU   AGGGC G    
target 5  A  AG   AAA    AAA     U G 3 GTF3C2-AS1
Start: 160  End: 180
Energy: -31.8 kcal/mol
Align Score: 0.008677
miRNA  3 AGCCA     C     U     C 5 hsa-miR-874-3p
               GGGAG CCG G CCCGU    
               CCCUC GGC C GGGCA    
target 5     C     U   A U     C 3 GTF3C2-AS1
Start: 426  End: 446
Energy: -31.7 kcal/mol
Align Score: 0.006907
miRNA  3 AGCCA     C     U     C 5 hsa-miR-874-3p
               GGGAG CCG G CCCGU    
               CCCUC GGC C GGGCA    
target 5     C     U   A U     C 3 GTF3C2-AS1
Start: 385  End: 405
Energy: -31.7 kcal/mol
Align Score: 0.006591
miRNA  3      A      C    G                5 hsa-miR-874-3p
           AGCC  GGGAG CC G        UCCCGUC    
           UUGG  CCCUC GG C        GGGGCAG    
target 5 C    GG     A  A AGGACACA       G 3 GTF3C2-AS1
Start: 226  End: 246
Energy: -34.7 kcal/mol
Align Score: 0.002197

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for GTF3C2-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-874-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for E2F3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p23.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.