Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

11p15.5

lncRNA

H19 ( ENSG00000130600)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

GPC1 (ENSG00000063660)

Disease

PCPG

FDR

9.76E-8

Reported as biomarkers
15

Circulating
13

Drug resistent
52

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' cgugUCGGGGGCAGGGAGGGa 5' hsa-miR-149-3p
              ||:|||: |||||||| 
target 5' ggtgAGTCCCT-TCCCTCCCc 3' H19
Start: 476  End: 495
Energy: -30.23 kcal/mol
Align Score: 163
miRNA  3' cgugUCGGGGGCAGGGAGGGa 5' hsa-miR-149-3p
              ||:|||: |||||||| 
target 5' ggtgAGTCCCT-TCCCTCCCc 3' H19
Start: 61  End: 80
Energy: -30.23 kcal/mol
Align Score: 163
miRNA  3' cgugUCGGGGGCAGGGAGGGa 5' hsa-miR-149-3p
              ||:|||: |||||||| 
target 5' ggtgAGTCCCT-TCCCTCCCc 3' H19
Start: 415  End: 434
Energy: -30.23 kcal/mol
Align Score: 163
miRNA  3' cgugUCGGGGGCAGGGAGGGa 5' hsa-miR-149-3p
              ||:|||: |||||||| 
target 5' ggtgAGTCCCT-TCCCTCCCc 3' H19
Start: 398  End: 417
Energy: -30.23 kcal/mol
Align Score: 163
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'     G          A      GA 5' hsa-miR-149-3p
           CGU UCGGG  GGC GGGAGG     
           GCA GGCCC  CCG CCCUCC     
target 5' U   G     GG          A  3' H19
Start: 585  End: 605
Energy: -36.6 kcal/mol
Align Score: 0.001289
miRNA  3'      U        C    A   A 5' hsa-miR-149-3p
           CGUG   CGGGGG AGGG GGG    
           GCAC   GCCCCC UCCC CCC    
target 5' A    CCU      A    A   A 3' H19
Start: 1112  End: 1132
Energy: -38.2 kcal/mol
Align Score: 0.002072
miRNA  3'     G          A      GA 5' hsa-miR-149-3p
           CGU UCGGG  GGC GGGAGG     
           GCA GGCCC  CCG CCCUCC     
target 5' U   G     GG          A  3' H19
Start: 1716  End: 1736
Energy: -36.6 kcal/mol
Align Score: 0.003938
miRNA  3'     G          A      GA 5' hsa-miR-149-3p
           CGU UCGGG  GGC GGGAGG     
           GCA GGCCC  CCG CCCUCC     
target 5' U   G     GG          A  3' H19
Start: 1617  End: 1637
Energy: -36.6 kcal/mol
Align Score: 0.003623
miRNA  3'     G          A      GA 5' hsa-miR-149-3p
           CGU UCGGG  GGC GGGAGG     
           GCA GGCCC  CCG CCCUCC     
target 5' U   G     GG          A  3' H19
Start: 1439  End: 1459
Energy: -36.6 kcal/mol
Align Score: 0.003187

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for H19

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GPC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 11p15.5

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.