Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

7q35

lncRNA

OR2A1-AS1 ( ENSG00000244479)

miRNA

hsa-let-7b-5p (MIMAT0000063)

mRNA

MTPN (ENSG00000105887)

Disease

PRAD

FDR

4.24E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' uuGGUGUGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            || :| || |||||||||| 
target 5' ttCCCTAGAAGCTACTACCTCt 3' OR2A1-AS1
Start: 525  End: 546
Energy: -24.04 kcal/mol
Align Score: 172
miRNA  3' uuGGUGUGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            || :| || |||||||||| 
target 5' ttCCCTAGAAGCTACTACCTCt 3' OR2A1-AS1
Start: 412  End: 433
Energy: -24.04 kcal/mol
Align Score: 172
miRNA  3' uuGGUGUGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            || :| || |||||||||| 
target 5' ttCCCTAGAAGCTACTACCTCt 3' OR2A1-AS1
Start: 281  End: 302
Energy: -24.04 kcal/mol
Align Score: 172
miRNA  3' uuGGUGUGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            || :| || |||||||||| 
target 5' ttCCCTAGAAGCTACTACCTCt 3' OR2A1-AS1
Start: 681  End: 702
Energy: -24.04 kcal/mol
Align Score: 172
miRNA  3' uuGGUGUGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            || :| || |||||||||| 
target 5' ttCCCTAGAAGCTACTACCTCt 3' OR2A1-AS1
Start: 539  End: 560
Energy: -24.04 kcal/mol
Align Score: 172
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'                            A    A    5' hsa-let-7b-5p
           UUGGUGUGU           UGGAUG  UGG GU    
           AGCCACACA           GCCUGC  GCC CA    
target 5' C         CCCCGAGCCCU      GG      G 3' OR2A1-AS1
Start: 21  End: 41
Energy: -30.8 kcal/mol
Align Score: 0.007686
miRNA  3' U           A         U 5' hsa-let-7b-5p
           UGGUGUGUUGG UGAUG GAG    
           GCCAUACAACC ACUAC CUU    
target 5' C           G     A   G 3' OR2A1-AS1
Start: 282  End: 302
Energy: -31.9 kcal/mol
Align Score: 0.003811
miRNA  3'                            A    A    5' hsa-let-7b-5p
           UUGGUGUGU           UGGAUG  UGG GU    
           AGCCACACA           GCCUGC  GCC CA    
target 5' C         CCCCGAGCCCU      GG      G 3' OR2A1-AS1
Start: 17  End: 37
Energy: -30.8 kcal/mol
Align Score: 0.008
miRNA  3                            A    A    5 hsa-let-7b-5p
           UUGGUGUGU           UGGAUG  UGG GU    
           AGCCACACA           GCCUGC  GCC CA    
target 5 C         CCCCGAGCCCU      GG      G 3 OR2A1-AS1
Start: 21  End: 41
Energy: -30.8 kcal/mol
Align Score: 0.007686
miRNA  3 U           A         U 5 hsa-let-7b-5p
           UGGUGUGUUGG UGAUG GAG    
           GCCAUACAACC ACUAC CUU    
target 5 C           G     A   G 3 OR2A1-AS1
Start: 282  End: 302
Energy: -31.9 kcal/mol
Align Score: 0.003811

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for OR2A1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-let-7b-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MTPN

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 7q35

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.