Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-let-7e-5p (MIMAT0000066)

mRNA

AURKB (ENSG00000178999)

Disease

PRAD

FDR

2.91E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'   UUGAUAUGUUGGAGGAUGGAGU 5' hsa-let-7e-5p
                          ||||||| 
target 5'  ACUUUUGGGUUUUGUCUACCUCA PCBP1-AS1
Start: 18  End: 25
Site type: 8mer-1a
Context++ Score: -0.428
RNAbybrid target site prediction
miRNA  3                            A    5 hsa-let-7e-5p
           UUGAU     AUGU  UGGAGGAUGG GU    
           GACUG     UGCA  GCCUCCUGCC CA    
target 5 A     CGGUC    UC          C  G 3 PCBP1-AS1
Start: 305  End: 325
Energy: -30.7 kcal/mol
Align Score: 0.009312
miRNA  3      U            A     U 5 hsa-let-7e-5p
           UUGA   AUGUUGGAGG UGGAG    
           GACU   UGCAACCUCC GCCUC    
target 5 C    CAC                C 3 PCBP1-AS1
Start: 83  End: 103
Energy: -30.7 kcal/mol
Align Score: 0.00594
miRNA  3      U            A     U 5 hsa-let-7e-5p
           UUGA   AUGUUGGAGG UGGAG    
           GACU   UGCAACCUCC GCCUC    
target 5 C    CAC                C 3 PCBP1-AS1
Start: 287  End: 307
Energy: -30.7 kcal/mol
Align Score: 0.008476
miRNA  3      U            A     U 5 hsa-let-7e-5p
           UUGA   AUGUUGGAGG UGGAG    
           GACU   UGCAACCUCC GCCUC    
target 5 C    CAC                C 3 PCBP1-AS1
Start: 258  End: 278
Energy: -30.7 kcal/mol
Align Score: 0.00764
miRNA  3 UUGAUA                   5 hsa-let-7e-5p
                UGUU GGAGGAUGGAGU    
                GCAA UCUCCUGCCUCA    
target 5      A    U            G 3 PCBP1-AS1
Start: 355  End: 375
Energy: -29.7 kcal/mol
Align Score: 0.008935

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-let-7e-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AURKB

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.