Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

4p16.3

lncRNA

NOP14-AS1 ( ENSG00000249673)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

GPC1 (ENSG00000063660)

Disease

PRAD

FDR

1.21E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' cgUGUCGGG-GGCAGGGAGGGa 5' hsa-miR-149-3p
            |||||:| | ||||||||| 
target 5' ttACAGCTCACAGTCCCTCCCg 3' NOP14-AS1
Start: 2066  End: 2087
Energy: -34.23 kcal/mol
Align Score: 174
miRNA  3' cgUGUCGGG-GGCAGGGAGGGa 5' hsa-miR-149-3p
            |||||:| | ||||||||| 
target 5' ttACAGCTCACAGTCCCTCCCg 3' NOP14-AS1
Start: 346  End: 367
Energy: -34.23 kcal/mol
Align Score: 174
miRNA  3' cgUGUCGGG-GGCAGGGAGGGa 5' hsa-miR-149-3p
            |||||:| | ||||||||| 
target 5' ttACAGCTCACAGTCCCTCCCg 3' NOP14-AS1
Start: 17  End: 38
Energy: -34.23 kcal/mol
Align Score: 174
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'    U        CA          A 5' hsa-miR-149-3p
           CG GUCGGGGG     GGGAGGG    
           GC CAGCUCCC     CCCUCCC    
target 5' A           ACCUC       A 3' NOP14-AS1
Start: 701  End: 721
Energy: -37.4 kcal/mol
Align Score: 0.003139
miRNA  3'    U        CA          A 5' hsa-miR-149-3p
           CG GUCGGGGG     GGGAGGG    
           GC CAGCUCCC     CCCUCCC    
target 5' A           ACCUC       A 3' NOP14-AS1
Start: 660  End: 680
Energy: -37.4 kcal/mol
Align Score: 0.001961
miRNA  3' C        GG          A 5' hsa-miR-149-3p
           GUGUCGGG   CAGGGAGGG    
           UACAGCUC   GUCCCUCCC    
target 5' U        ACA         G 3' NOP14-AS1
Start: 346  End: 366
Energy: -39.4 kcal/mol
Align Score: 0.001227
miRNA  3' C        GG          A 5' hsa-miR-149-3p
           GUGUCGGG   CAGGGAGGG    
           UACAGCUC   GUCCCUCCC    
target 5' U        ACA         G 3' NOP14-AS1
Start: 17  End: 37
Energy: -39.4 kcal/mol
Align Score: 0.000095
miRNA  3'        G        G          A 5' hsa-miR-149-3p
           CGUGUC      GGG CAG GGAGGG    
           GCACAG      CCC GUC CCUCCC    
target 5' G      ACGCAA   A   U      A 3' NOP14-AS1
Start: 105  End: 125
Energy: -37 kcal/mol
Align Score: 0.000293

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for NOP14-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GPC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 4p16.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.