Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

21q22.3

lncRNA

MCM3AP-AS1 ( ENSG00000215424)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

STIM1 (ENSG00000167323)

Disease

PCPG

FDR

4.91E-9

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CU                               A 5 hsa-miR-185-3p
            GGUCUCC           UUUCGG UCGGGG    
            CUAGAGG           GGAGCC GGCCUC    
target 5  U       CUUGCGUCCCG      C      G 3 MCM3AP-AS1
Start: 2  End: 22
Energy: -31.2 kcal/mol
Align Score: 0.008482
miRNA  3      U    UU    U     A 5 hsa-miR-185-3p
           CUGG CUCC  UCGG CGGGG    
           GACC GAGG  GGCC GCCCC    
target 5 U               U     A 3 MCM3AP-AS1
Start: 374  End: 394
Energy: -35.8 kcal/mol
Align Score: 0.001161
miRNA  3 CU GU               G A 5 hsa-miR-185-3p
            G  CUCCUUUC GGUCGG G    
            U  GAGGAGGG CCAGCC C    
target 5  U GU        U      G G 3 MCM3AP-AS1
Start: 14  End: 34
Energy: -33.5 kcal/mol
Align Score: 0.002879
miRNA  3                                A 5 hsa-miR-185-3p
           CUGG  UCUCC   UUUCGG    UCGGGG    
           GACC  AGGGG   GAAGCC    AGCCCC    
target 5 G    AC     CCA      CUGG      G 3 MCM3AP-AS1
Start: 89  End: 109
Energy: -35.6 kcal/mol
Align Score: 0.005866

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MCM3AP-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for STIM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 21q22.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.