Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10q22.2

lncRNA

PPP3CB-AS1 ( ENSG00000221817)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

FOXO1 (ENSG00000150907)

Disease

PRAD

FDR

5.74E-14

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U     AA             G      5 hsa-miR-370-3p
           GGUCC  GGUGGGG    UC UCCG    
           CCAGG  CCACUCC    GG AGGC    
target 5 C     GG       CCAA  G    A 3 PPP3CB-AS1
Start: 141  End: 161
Energy: -37.8 kcal/mol
Align Score: 0.001097
miRNA  3                                           U  G 5 hsa-miR-370-3p
           UGGUCC           AAGGUGGG            GUCG CC    
           GCCGGG           UUCCACCC            UAGC GG    
target 5 U      CUAACCGAUUC        AAGCCUCCUAAG    U  G 3 PPP3CB-AS1
Start: 445  End: 465
Energy: -31.8 kcal/mol
Align Score: 0.006175
miRNA  3     U         G        G      5 hsa-miR-370-3p
           UGG   CCAAGGU    GGGUC UCCG    
           GCC   GGUUCCA    CUCGG AGGC    
target 5 C   UAU       GCUA     G    U 3 PPP3CB-AS1
Start: 921  End: 941
Energy: -35.2 kcal/mol
Align Score: 0.003285
miRNA  3    G          GGU  U     5 hsa-miR-370-3p
           UG UCCAAGGUGG   CG CCG    
           AC GGGUUUCACC   GU GGC    
target 5 G  G          AU   U   C 3 PPP3CB-AS1
Start: 577  End: 597
Energy: -31.1 kcal/mol
Align Score: 0.0081
miRNA  3        A                    G 5 hsa-miR-370-3p
           UGGUCC  AGG   UGGGGUC  GUCC    
           ACCAGG  UUC   ACCCUGG  CAGG    
target 5 G      GG   GGG       AA    A 3 PPP3CB-AS1
Start: 358  End: 378
Energy: -30.5 kcal/mol
Align Score: 0.007291

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PPP3CB-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for FOXO1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10q22.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.