Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

7q32.3

lncRNA

LINC-PINT ( ENSG00000231721)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

TCEAL1 (ENSG00000172465)

Disease

PRAD

FDR

1.17E-5

Reported as biomarkers
3

Circulating
1

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3        A                  G 5 hsa-miR-370-3p
           UGGUCC AGG   UGGGGUC GUCC    
           GCCGGG UCC   GCCCUGG CGGG    
target 5 A      G   UUG       C    G 3 LINC-PINT
Start: 102  End: 122
Energy: -35.2 kcal/mol
Align Score: 0.001615
miRNA  3            A                              5 hsa-miR-370-3p
           UGGUC   CA            GGUGGGGU   CGUCCG    
           ACCAG   GU            CCACCCCA   GCAGGU    
target 5 U     ACA  GUCUCUUCAACC        GGC      U 3 LINC-PINT
Start: 166  End: 186
Energy: -33.4 kcal/mol
Align Score: 0.007569
miRNA  3        AA                                         5 hsa-miR-370-3p
           UGGUCC              GGUGGGGUC             GUCCG    
           GCCAGG              CCAUCUCAG             CAGGC    
target 5 A      AAGAGGGACUGGAA         AAGCCAUGCCCCU     U 3 LINC-PINT
Start: 96  End: 116
Energy: -30.6 kcal/mol
Align Score: 0.006175
miRNA  3 U      A G     U        5 hsa-miR-370-3p
           GGUCCA G UGGGG CGUCCG    
           CCAGGU U ACUUU GCAGGC    
target 5 C      G G            A 3 LINC-PINT
Start: 137  End: 157
Energy: -31.5 kcal/mol
Align Score: 0.005645
miRNA  3        A                  G 5 hsa-miR-370-3p
           UGGUCC AGG   UGGGGUC GUCC    
           GCCGGG UCC   GCCCUGG CGGG    
target 5 A      G   UUG       C    G 3 LINC-PINT
Start: 18  End: 38
Energy: -35.2 kcal/mol
Align Score: 0.00231

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC-PINT

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TCEAL1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 7q32.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.