Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-766-3p (MIMAT0003888)

mRNA

BAX (ENSG00000087088)

Disease

PRAD

FDR

9.94E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' cgaCUCCGACA----CCCCGACCUCa 5' hsa-miR-766-3p
             || |:|||    |||||||||| 
target 5' gagGAAGTTGTTCTGGGGGCTGGAGa 3' PCBP1-AS1
Start: 1769  End: 1794
Energy: -32.33 kcal/mol
Align Score: 162
miRNA  3' cgaCUCCGACA----CCCCGACCUCa 5' hsa-miR-766-3p
             || |:|||    |||||||||| 
target 5' gagGAAGTTGTTCTGGGGGCTGGAGa 3' PCBP1-AS1
Start: 1199  End: 1224
Energy: -32.33 kcal/mol
Align Score: 162
miRNA  3' cgacUCCGACACCCCGACCUCa 5' hsa-miR-766-3p
              :|||||| | ||||||| 
target 5' gcatGGGCTGTTGTGCTGGAGa 3' PCBP1-AS1
Start: 379  End: 400
Energy: -27.01 kcal/mol
Align Score: 170
miRNA  3' cgacUCCGACACCCCGACCUCa 5' hsa-miR-766-3p
              :|||||| | ||||||| 
target 5' gcatGGGCTGTTGTGCTGGAGa 3' PCBP1-AS1
Start: 379  End: 400
Energy: -27.01 kcal/mol
Align Score: 170
miRNA  3' cgacUCCGACACCCCGACCUCa 5' hsa-miR-766-3p
              :|||||| | ||||||| 
target 5' gcatGGGCTGTTGTGCTGGAGa 3' PCBP1-AS1
Start: 40  End: 61
Energy: -27.01 kcal/mol
Align Score: 170
TargetScan target site prediction
miRNA  3'  CGACUCCGACACCCCGACCUCA 5' hsa-miR-766-3p
                ||||||   ||||||| 
target 5' AGCAUGGGCUGUUGUGCUGGAGA PCBP1-AS1
Start: 54  End: 61
Site type: 8mer-1a
Context++ Score: -0.455
miRNA  3'  CGACUCCGACACCCCGACCUCA 5' hsa-miR-766-3p
                ||||||   ||||||| 
target 5' AGCAUGGGCUGUUGUGCUGGAGA PCBP1-AS1
Start: 393  End: 400
Site type: 8mer-1a
Context++ Score: -0.402
miRNA  3'  CGACUCCGACACCCCGACCUCA 5' hsa-miR-766-3p
                ||||||   ||||||| 
target 5' AGCAUGGGCUGUUGUGCUGGAGA PCBP1-AS1
Start: 78  End: 85
Site type: 8mer-1a
Context++ Score: -0.446
miRNA  3'  CGACUCCGACACCCCGACCUCA 5' hsa-miR-766-3p
                ||||||   ||||||| 
target 5' AGCAUGGGCUGUUGUGCUGGAGA PCBP1-AS1
Start: 36  End: 43
Site type: 8mer-1a
Context++ Score: -0.459
miRNA  3'  CGACUCCGACACCCCGACCUCA 5' hsa-miR-766-3p
                ||||||   ||||||| 
target 5' AGCAUGGGCUGUUGUGCUGGAGA PCBP1-AS1
Start: 194  End: 201
Site type: 8mer-1a
Context++ Score: -0.419
RNAbybrid target site prediction
miRNA  3' CGA               A          A 5' hsa-miR-766-3p
             CUCC        GAC CCCCGACCUC    
             GAGG        CUG GGGGCUGGAG    
target 5'   A    AAGUUGUU              A 3' PCBP1-AS1
Start: 1198  End: 1218
Energy: -35.6 kcal/mol
Align Score: 0.003703
miRNA  3' CG     GA         A      A 5' hsa-miR-766-3p
            ACUCC   C ACCCCG   CCUC    
            UGGGG   G UGGGGC   GGGG    
target 5'  G     AAG A      CAA    A 3' PCBP1-AS1
Start: 326  End: 346
Energy: -30.1 kcal/mol
Align Score: 0.009837
miRNA  3'    A       A A     A                    5' hsa-miR-766-3p
           CG   CUCCG C CCCCG              CCUCA    
           GC   GAGGC G GGGGC              GGAGU    
target 5' G  AGG     C A     AGCAGUGCGGACAG     C 3' PCBP1-AS1
Start: 465  End: 485
Energy: -30.8 kcal/mol
Align Score: 0.007469
miRNA  3'    AC       C C       A 5' hsa-miR-766-3p
           CG  UCCGACA C CGACCUC    
           GC  GGGCUGU G GCUGGAG    
target 5' A  AU       U U       A 3' PCBP1-AS1
Start: 378  End: 398
Energy: -32.3 kcal/mol
Align Score: 0.007413
miRNA  3'               C                     A 5' hsa-miR-766-3p
           CGACU    CCGA          ACCCC GACCUC    
           GCUGG    GGCU          UGGGG CUGGGG    
target 5' U     UUCU    CCAGAGGGAC     U      C 3' PCBP1-AS1
Start: 32  End: 52
Energy: -31.2 kcal/mol
Align Score: 0.003787

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-766-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BAX

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.