Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-125a-5p (MIMAT0000443)

mRNA

ERBB2 (ENSG00000141736)

Disease

SARC

FDR

4.40E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3' AGUGUCCAAUUUCCCAGAGUCCCU 5' hsa-miR-125a-5p
                          ||||||| 
target 5'  CGUGCUUCACAAUCUCUCAGGGA PCBP1-AS1
Start: 52  End: 59
Site type: 8mer-1a
Context++ Score: -0.412
miRNA  3' AGUGUCCAAUUUCCCAGAGUCCCU 5' hsa-miR-125a-5p
                          ||||||| 
target 5'  CGUGCUUCACAAUCUCUCAGGGA PCBP1-AS1
Start: 69  End: 76
Site type: 8mer-1a
Context++ Score: -0.408
RNAbybrid target site prediction
miRNA  3 A                     G      CU 5 hsa-miR-125a-5p
           GUGUCCA    AUUUCCCAGA    UCC     
           CACAGGU    UGAGGGGUUU    AGG     
target 5 C       UGGU          AACA   C  3 PCBP1-AS1
Start: 44  End: 64
Energy: -31.7 kcal/mol
Align Score: 0.008374
miRNA  3         AA           CCCU 5 hsa-miR-125a-5p
           AGUGUCC  UUUCCCAGAGU       
           UCAUGGG  AAAGGGUCUCA       
target 5 U       AA           C    3 PCBP1-AS1
Start: 18  End: 38
Energy: -31.4 kcal/mol
Align Score: 0.006713
miRNA  3 A                     G      CU 5 hsa-miR-125a-5p
           GUGUCCA    AUUUCCCAGA    UCC     
           CACAGGU    UGAGGGGUUU    AGG     
target 5 C       UGGU          AACA   C  3 PCBP1-AS1
Start: 23  End: 43
Energy: -31.7 kcal/mol
Align Score: 0.008903
miRNA  3 A                     G      CU 5 hsa-miR-125a-5p
           GUGUCCA    AUUUCCCAGA    UCC     
           CACAGGU    UGAGGGGUUU    AGG     
target 5 C       UGGU          AACA   C  3 PCBP1-AS1
Start: 261  End: 281
Energy: -31.7 kcal/mol
Align Score: 0.009786
miRNA  3 A                     G      CU 5 hsa-miR-125a-5p
           GUGUCCA    AUUUCCCAGA    UCC     
           CACAGGU    UGAGGGGUUU    AGG     
target 5 C       UGGU          AACA   C  3 PCBP1-AS1
Start: 247  End: 267
Energy: -31.7 kcal/mol
Align Score: 0.009641

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-125a-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERBB2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.