Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17p11.2

lncRNA

CCDC144NL-AS1 ( ENSG00000233098)

miRNA

hsa-miR-146b-3p (MIMAT0004766)

mRNA

NPAS4 (ENSG00000174576)

Disease

SARC

FDR

1.48E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ggucUUGACUC-AGGUGUCCCGu 5' hsa-miR-146b-3p
              ||:  || |||||||||| 
target 5' ctccAATGCAGCTCCACAGGGCc 3' CCDC144NL-AS1
Start: 280  End: 302
Energy: -26.2 kcal/mol
Align Score: 161
miRNA  3' ggucUUGACUC-AGGUGUCCCGu 5' hsa-miR-146b-3p
              ||:  || |||||||||| 
target 5' ctccAATGCAGCTCCACAGGGCc 3' CCDC144NL-AS1
Start: 789  End: 811
Energy: -26.2 kcal/mol
Align Score: 161
miRNA  3' ggucUUGACUC-AGGUGUCCCGu 5' hsa-miR-146b-3p
              ||:  || |||||||||| 
target 5' ctccAATGCAGCTCCACAGGGCc 3' CCDC144NL-AS1
Start: 437  End: 459
Energy: -26.2 kcal/mol
Align Score: 161
miRNA  3' ggucUUGACUC-AGGUGUCCCGu 5' hsa-miR-146b-3p
              ||:  || |||||||||| 
target 5' ctccAATGCAGCTCCACAGGGCc 3' CCDC144NL-AS1
Start: 646  End: 668
Energy: -26.2 kcal/mol
Align Score: 161
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'                                        U 5' hsa-miR-146b-3p
           GGUC UUGAC               UC AGGUGUCCCG    
           CCAG AGCUG               AG UCCACAGGGC    
target 5' A    C     CUGUCUCUCCAAUGC  C          C 3' CCDC144NL-AS1
Start: 263  End: 283
Energy: -34.1 kcal/mol
Align Score: 0.001761
miRNA  3'       UGAC             U 5' hsa-miR-146b-3p
           GGUCU    UCAGGUGU CCCG    
           CCAGA    AGUCCACA GGGU    
target 5' C     U           A    G 3' CCDC144NL-AS1
Start: 481  End: 501
Energy: -31.5 kcal/mol
Align Score: 0.005231
miRNA  3'                                        U 5' hsa-miR-146b-3p
           GGUC UUGAC               UC AGGUGUCCCG    
           CCAG AGCUG               AG UCCACAGGGC    
target 5' A    C     CUGUCUCUCCAAUGC  C          C 3' CCDC144NL-AS1
Start: 772  End: 792
Energy: -34.1 kcal/mol
Align Score: 0.008307
miRNA  3'                                        U 5' hsa-miR-146b-3p
           GGUC UUGAC               UC AGGUGUCCCG    
           CCAG AGCUG               AG UCCACAGGGC    
target 5' A    C     CUGUCUCUCCAAUGC  C          C 3' CCDC144NL-AS1
Start: 420  End: 440
Energy: -34.1 kcal/mol
Align Score: 0.002988
miRNA  3'            U                      5' hsa-miR-146b-3p
           GGUC UUGAC  CAGG       UGUCCCGU    
           CCAG AGCUG  GUCU       GCAGGGCA    
target 5' A    C     CU    CUCCAAU        A 3' CCDC144NL-AS1
Start: 393  End: 413
Energy: -33.9 kcal/mol
Align Score: 0.003907

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CCDC144NL-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-146b-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for NPAS4

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17p11.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.