Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

22q12.1

lncRNA

TTC28-AS1 ( ENSG00000235954)

miRNA

hsa-miR-146b-3p (MIMAT0004766)

mRNA

NPAS4 (ENSG00000174576)

Disease

SARC

FDR

2.36E-6

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ggUCUUGACU-CAGGUGUCCCGu 5' hsa-miR-146b-3p
            ||: |  | ||||||||||| 
target 5' gaAGGTCCCAGGTCCACAGGGCc 3' TTC28-AS1
Start: 4729  End: 4751
Energy: -27.35 kcal/mol
Align Score: 163
TargetScan target site prediction
miRNA  3'  GGUCUUGACUCAGGUGUCCCGU 5' hsa-miR-146b-3p
                         ||||||| 
target 5' ACUACUAACGAACAUACAGGGCA TTC28-AS1
Start: 222  End: 229
Site type: 8mer-1a
Context++ Score: -0.431
miRNA  3'  GGUCUUGACUCAGGUGUCCCGU 5' hsa-miR-146b-3p
                         ||||||| 
target 5' ACUACUAACGAACAUACAGGGCA TTC28-AS1
Start: 222  End: 229
Site type: 8mer-1a
Context++ Score: -0.431
RNAbybrid target site prediction
miRNA  3'         A  U  G            5' hsa-miR-146b-3p
           GGUCUUG  C CA  GUGUCCCGU    
           UCAGAGC  G GU  CACAGGGCA    
target 5' C       AG U  AA         U 3' TTC28-AS1
Start: 395  End: 415
Energy: -32.1 kcal/mol
Align Score: 0.007606
miRNA  3'         A  U  G            5' hsa-miR-146b-3p
           GGUCUUG  C CA  GUGUCCCGU    
           UCAGAGC  G GU  CACAGGGCA    
target 5' C       AG U  AA         U 3' TTC28-AS1
Start: 436  End: 456
Energy: -32.1 kcal/mol
Align Score: 0.007511
miRNA  3'         A  U  G            5' hsa-miR-146b-3p
           GGUCUUG  C CA  GUGUCCCGU    
           UCAGAGC  G GU  CACAGGGCA    
target 5' C       AG U  AA         U 3' TTC28-AS1
Start: 519  End: 539
Energy: -32.1 kcal/mol
Align Score: 0.007192
miRNA  3         A  U  G            5 hsa-miR-146b-3p
           GGUCUUG  C CA  GUGUCCCGU    
           UCAGAGC  G GU  CACAGGGCA    
target 5 C       AG U  AA         U 3 TTC28-AS1
Start: 395  End: 415
Energy: -32.1 kcal/mol
Align Score: 0.007606
miRNA  3         A  U  G            5 hsa-miR-146b-3p
           GGUCUUG  C CA  GUGUCCCGU    
           UCAGAGC  G GU  CACAGGGCA    
target 5 C       AG U  AA         U 3 TTC28-AS1
Start: 436  End: 456
Energy: -32.1 kcal/mol
Align Score: 0.007511

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for TTC28-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-146b-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for NPAS4

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 22q12.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.