Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q13

lncRNA

MIR4435-2HG ( ENSG00000172965)

miRNA

hsa-miR-149-5p (MIMAT0000450)

mRNA

IL6 (ENSG00000136244)

Disease

SARC

FDR

2.26E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 C            GC                5 hsa-miR-149-5p
           CCUCACUUCUGU       CUCGGU CU    
           GGAGUGAGGAUA       GAGCCA GA    
target 5 C            AAGAGAA      U  C 3 MIR4435-2HG
Start: 1420  End: 1440
Energy: -34.1 kcal/mol
Align Score: 0.00777
miRNA  3       A                  G                5 hsa-miR-149-5p
           CCCUC              CUUCU UGCCUC   GGUCU    
           GGGAG              GAGGA AUGGAG   CCAGG    
target 5 A     CUGGAGCAGAUGAG     G      GUC     A 3 MIR4435-2HG
Start: 574  End: 594
Energy: -31.6 kcal/mol
Align Score: 0.009469
miRNA  3 C    A          G    G      5 hsa-miR-149-5p
           CCUC CU   UCUGU CCUC GUCU    
           GGAG GG   GGACA GGAG CAGA    
target 5 A    C  CCA     G         A 3 MIR4435-2HG
Start: 576  End: 596
Energy: -31.3 kcal/mol
Align Score: 0.008081
miRNA  3 CCC                         5 hsa-miR-149-5p
             UCACUUCU  GUG CCUCGGUCU    
             AGUGGAGG  CAC GGGGCCGGA    
target 5   C        GC   U         G 3 MIR4435-2HG
Start: 424  End: 444
Energy: -33.5 kcal/mol
Align Score: 0.004356
miRNA  3 CCC                         5 hsa-miR-149-5p
             UCACUUCU  GUG CCUCGGUCU    
             AGUGGAGG  CAC GGGGCCGGA    
target 5   C        GC   U         G 3 MIR4435-2HG
Start: 206  End: 226
Energy: -33.5 kcal/mol
Align Score: 0.002802

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MIR4435-2HG

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for IL6

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q13

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.