Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-23a-5p (MIMAT0004496)

mRNA

APAF1 (ENSG00000120868)

Disease

SARC

FDR

9.66E-15

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U     GUA      C         5 hsa-miR-23a-5p
           UUAGG   GGGGUC UUGG GG    
           GAUCC   CCCCAG AGCC CU    
target 5 U     AG       A    A  G 3 ZEB1-AS1
Start: 219  End: 239
Energy: -30.2 kcal/mol
Align Score: 0.005782
miRNA  3 U        AG         G    5 hsa-miR-23a-5p
           UUAG GGU  GGGUCCUUG GG    
           GGUC CUA  CCCAGGGAC CC    
target 5 C    U   AG         G  U 3 ZEB1-AS1
Start: 150  End: 170
Energy: -32.5 kcal/mol
Align Score: 0.003166
miRNA  3 UUU    U              G    5 hsa-miR-23a-5p
             AGGG AGG   GGUCCUUG GG    
             UCCC UCC   CCAGGGAC CC    
target 5   U    U   CUU        G  U 3 ZEB1-AS1
Start: 361  End: 381
Energy: -32.9 kcal/mol
Align Score: 0.003369
miRNA  3 UUU    U              G    5 hsa-miR-23a-5p
             AGGG AGG   GGUCCUUG GG    
             UCCC UCC   CCAGGGAC CC    
target 5   U    U   CUU        G  U 3 ZEB1-AS1
Start: 459  End: 479
Energy: -32.9 kcal/mol
Align Score: 0.003481
miRNA  3 UU      A               G 5 hsa-miR-23a-5p
            UAGGGU   G GGGUCCUUGGG    
            GUUCCG   C CCCGGGGGCCU    
target 5  U      CGG U           G 3 ZEB1-AS1
Start: 107  End: 127
Energy: -31.2 kcal/mol
Align Score: 0.004938

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-23a-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for APAF1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.