Basic Info

Starting a new search ...

Basic Information for the CNV-ceRNA event

Cytoband

11q13.1

lncRNA

NEAT1 ( ENSG00000245532)

miRNA

hsa-miR-339-5p (MIMAT0000764)

mRNA

BCL6 (ENSG00000113916)

Disease

SARC

FDR

1.88E-3

Reported as biomarkers
7

Circulating
6

Drug resistent
41

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' gcaCUCGAGGACCUC---CUGUCCCu 5' hsa-miR-339-5p
             |:|||:| ||:|   ||||||| 
target 5' tcaGGGCTTCAGGGGACAGACAGGGa 3' NEAT1
Start: 86  End: 111
Energy: -31.53 kcal/mol
Align Score: 163
miRNA  3' gcaCUCGAGGACCUC---CUGUCCCu 5' hsa-miR-339-5p
             |:|||:| ||:|   ||||||| 
target 5' tcaGGGCTTCAGGGGACAGACAGGGa 3' NEAT1
Start: 62  End: 87
Energy: -31.53 kcal/mol
Align Score: 163
miRNA  3' gcaCUCGAGGACCUC---CUGUCCCu 5' hsa-miR-339-5p
             |:|||:| ||:|   ||||||| 
target 5' tcaGGGCTTCAGGGGACAGACAGGGa 3' NEAT1
Start: 60  End: 85
Energy: -31.53 kcal/mol
Align Score: 163
TargetScan target site prediction
miRNA  3'   GCACUCGAGGACCUCCUGUCCCU 5' hsa-miR-339-5p
                           ||||||| 
target 5'   GGGCUUCAGGGGACAGACAGGGA NEAT1
Start: 80  End: 87
Site type: 8mer-1a
Context++ Score: -0.401
miRNA  3'   GCACUCGAGGACCUCCUGUCCCU 5' hsa-miR-339-5p
                           ||||||| 
target 5'   GGGCUUCAGGGGACAGACAGGGA NEAT1
Start: 78  End: 85
Site type: 8mer-1a
Context++ Score: -0.402
miRNA  3'   GCACUCGAGGACCUCCUGUCCCU 5' hsa-miR-339-5p
                           ||||||| 
target 5'   GGGCUUCAGGGGACAGACAGGGA NEAT1
Start: 80  End: 87
Site type: 8mer-1a
Context++ Score: -0.401
miRNA  3'   GCACUCGAGGACCUCCUGUCCCU 5' hsa-miR-339-5p
                           ||||||| 
target 5'   GGGCUUCAGGGGACAGACAGGGA NEAT1
Start: 78  End: 85
Site type: 8mer-1a
Context++ Score: -0.402
RNAbybrid target site prediction
miRNA  3' GCA     G A       U      5' hsa-miR-339-5p
             CUCGA G CCUCCUG CCCU    
             GGGCU C GGAGGGC GGGA    
target 5'   A     G A       C    G 3' NEAT1
Start: 455  End: 475
Energy: -36 kcal/mol
Align Score: 0.004973
miRNA  3' GCA       A                 5' hsa-miR-339-5p
             CUCGAGG CCUC   CUGUCCCU    
             GGGCUUC GGGG   GACAGGGA    
target 5'   A       A    ACA        G 3' NEAT1
Start: 62  End: 82
Energy: -35.7 kcal/mol
Align Score: 0.001018
miRNA  3' GC       G         CCCU 5' hsa-miR-339-5p
            ACUCGAG ACCUCCUGU       
            UGAGCUU UGGGGGGCA       
target 5'  A       A         A    3' NEAT1
Start: 353  End: 373
Energy: -31.8 kcal/mol
Align Score: 0.005565
miRNA  3 GCA     G A       U      5 hsa-miR-339-5p
             CUCGA G CCUCCUG CCCU    
             GGGCU C GGAGGGC GGGA    
target 5   A     G A       C    G 3 NEAT1
Start: 455  End: 475
Energy: -36 kcal/mol
Align Score: 0.004973
miRNA  3 GCA       A                 5 hsa-miR-339-5p
             CUCGAGG CCUC   CUGUCCCU    
             GGGCUUC GGGG   GACAGGGA    
target 5   A       A    ACA        G 3 NEAT1
Start: 62  End: 82
Energy: -35.7 kcal/mol
Align Score: 0.001018

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for NEAT1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-339-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BCL6

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 11q13.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.