Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17p11.2

lncRNA

CCDC144NL-AS1 ( ENSG00000233098)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

FOXO1 (ENSG00000150907)

Disease

SARC

FDR

6.11E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3        A          CGU     5 hsa-miR-370-3p
           UGGUCC  AGGUGGGGU   CCG    
           GCCAGG  UUCACCCCA   GGC    
target 5 U      GC         U     C 3 CCDC144NL-AS1
Start: 1060  End: 1080
Energy: -35.4 kcal/mol
Align Score: 0.005813
miRNA  3    GU CAA                   5 hsa-miR-370-3p
           UG  C   GGUGGGG   UCGUCCG    
           AC  G   CCACCCC   AGCAGGC    
target 5 C  GU AGC       CAC       G 3 CCDC144NL-AS1
Start: 577  End: 597
Energy: -35.3 kcal/mol
Align Score: 0.002293
miRNA  3        AA                             5 hsa-miR-370-3p
           UGGUCC  GGU          GGGGU   CGUCCG    
           GCCAGG  UCA          UCCCA   GUAGGC    
target 5 G      CC   GAGAAGGGUG     GAU      A 3 CCDC144NL-AS1
Start: 36  End: 56
Energy: -31.5 kcal/mol
Align Score: 0.005231
miRNA  3       CAA          UC     5 hsa-miR-370-3p
           UGGUC   GGUGGGGUCG   CG    
           ACCAG   CCACUCCAGC   GC    
target 5 C     AGG          UUC  G 3 CCDC144NL-AS1
Start: 684  End: 704
Energy: -34.9 kcal/mol
Align Score: 0.002191
miRNA  3        A          U     C    G 5 hsa-miR-370-3p
           UGGUCC        AGG GGGGU GUCC    
           ACCAGG        UCC CUCCA CAGG    
target 5 C      GAACCUGC         C    A 3 CCDC144NL-AS1
Start: 182  End: 202
Energy: -31.1 kcal/mol
Align Score: 0.007966

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CCDC144NL-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for FOXO1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17p11.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.