Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-639 (MIMAT0003309)

mRNA

FOXC1 (ENSG00000054598)

Disease

SARC

FDR

7.51E-16

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3        GAG G             A 5 hsa-miR-639
           UGUCGC   C UUGGCG  UCGCU    
           GCGGCG   G AGCCGC  GGCGG    
target 5 G          G      UA     A 3 ZEB1-AS1
Start: 145  End: 165
Energy: -29.9 kcal/mol
Align Score: 0.006894
miRNA  3 UG    GA                G  A 5 hsa-miR-639
            UCGC  GCG     UUGGCGUC CU    
            GGCG  UGC     AACCGUAG GA    
target 5  A    GA   CGGGA        G  C 3 ZEB1-AS1
Start: 77  End: 97
Energy: -30.3 kcal/mol
Align Score: 0.00985
miRNA  3 U        C  UG        CUA 5 hsa-miR-639
           GUCGCGAG GU  GCG  UCG      
           CAGCGCUC CG  CGU  GGC      
target 5 U           UG   CC   C   3 ZEB1-AS1
Start: 12  End: 32
Energy: -31.3 kcal/mol
Align Score: 0.005323
miRNA  3        GAG G            A 5 hsa-miR-639
           UGUCGC   C UUG GCGUCGCU    
           ACGGCG   G GAC CGCGGCGA    
target 5 G      A       A        C 3 ZEB1-AS1
Start: 301  End: 321
Energy: -30.8 kcal/mol
Align Score: 0.007875
miRNA  3 UGU     G  U              CUA 5 hsa-miR-639
             CGCGA CG       UGGCGUCG      
             GCGCU GC       GCCGCGGC      
target 5   C     G  CACACCC        U   3 ZEB1-AS1
Start: 152  End: 172
Energy: -32.4 kcal/mol
Align Score: 0.004452

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-639

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for FOXC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.