Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

7q32.3

lncRNA

LINC-PINT ( ENSG00000231721)

miRNA

hsa-miR-1181 (MIMAT0005826)

mRNA

STAT3 (ENSG00000168610)

Disease

SKCM

FDR

6.83E-8

Reported as biomarkers
3

Circulating
1

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 G   A        A   C G         5 hsa-miR-1181
           CCG     GCCC CCG C CU  GCC    
           GGC     CGGG GGC G GA  CGG    
target 5 G   GACGC    G   A G  GC   G 3 LINC-PINT
Start: 81  End: 101
Energy: -30.7 kcal/mol
Align Score: 0.008237
miRNA  3       A       G     G    5 hsa-miR-1181
           GC CG GCCCACC CCGCU CC    
           CG GC UGGGUGG GGCGA GG    
target 5 G  C  C             A  G 3 LINC-PINT
Start: 111  End: 131
Energy: -34.5 kcal/mol
Align Score: 0.00492
miRNA  3      AG      G   CU     5 hsa-miR-1181
           GCCG  CCCACC CCG  GCC    
           CGGC  GGGUGG GGC  UGG    
target 5 G    G                U 3 LINC-PINT
Start: 341  End: 361
Energy: -31.4 kcal/mol
Align Score: 0.00344
miRNA  3 G   A        A   C G         5 hsa-miR-1181
           CCG     GCCC CCG C CU  GCC    
           GGC     CGGG GGC G GA  CGG    
target 5 G   GACGC    G   A G  GC   G 3 LINC-PINT
Start: 117  End: 137
Energy: -30.7 kcal/mol
Align Score: 0.007407

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC-PINT

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1181

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for STAT3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 7q32.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.