Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17q21.31

lncRNA

MAP3K14-AS1 ( ENSG00000267278)

miRNA

hsa-miR-1226-3p (MIMAT0005577)

mRNA

MUC1 (ENSG00000185499)

Disease

SKCM

FDR

6.08E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' gaUCCCUUGUGUCCCGACCACu 5' hsa-miR-1226-3p
            ||||:||::  |||||||| 
target 5' agAGGGGACGT--GGCTGGTGg 3' MAP3K14-AS1
Start: 81  End: 100
Energy: -31.7 kcal/mol
Align Score: 165
miRNA  3' gaUCCCUUGUGUCCCGACCACu 5' hsa-miR-1226-3p
            ||||:||::  |||||||| 
target 5' agAGGGGACGT--GGCTGGTGg 3' MAP3K14-AS1
Start: 52  End: 71
Energy: -31.7 kcal/mol
Align Score: 165
miRNA  3' gaUCCCUUGUGUCCCGACCACu 5' hsa-miR-1226-3p
            ||||:||::  |||||||| 
target 5' agAGGGGACGT--GGCTGGTGg 3' MAP3K14-AS1
Start: 148  End: 167
Energy: -31.7 kcal/mol
Align Score: 165
miRNA  3' gaUCCCUUGUGUCCCGACCACu 5' hsa-miR-1226-3p
            ||||:||::  |||||||| 
target 5' agAGGGGACGT--GGCTGGTGg 3' MAP3K14-AS1
Start: 41  End: 60
Energy: -31.7 kcal/mol
Align Score: 165
miRNA  3' gaUCCCUUGUGUCCCGACCACu 5' hsa-miR-1226-3p
            ||||:||::  |||||||| 
target 5' agAGGGGACGT--GGCTGGTGg 3' MAP3K14-AS1
Start: 113  End: 132
Energy: -31.7 kcal/mol
Align Score: 165
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'          GUG        ACU 5' hsa-miR-1226-3p
           GAUCCCUU   UCCCGACC      
           CUGGGGAA   GGGGCUGG      
target 5' G                   A   3' MAP3K14-AS1
Start: 344  End: 364
Energy: -33.3 kcal/mol
Align Score: 0.002178
miRNA  3'          GUG        ACU 5' hsa-miR-1226-3p
           GAUCCCUU   UCCCGACC      
           CUGGGGAA   GGGGCUGG      
target 5' G                   A   3' MAP3K14-AS1
Start: 249  End: 269
Energy: -33.3 kcal/mol
Align Score: 0.002792
miRNA  3'          GUG        ACU 5' hsa-miR-1226-3p
           GAUCCCUU   UCCCGACC      
           CUGGGGAA   GGGGCUGG      
target 5' G                   A   3' MAP3K14-AS1
Start: 249  End: 269
Energy: -33.3 kcal/mol
Align Score: 0.005354
miRNA  3'          GUG        ACU 5' hsa-miR-1226-3p
           GAUCCCUU   UCCCGACC      
           CUGGGGAA   GGGGCUGG      
target 5' G                   A   3' MAP3K14-AS1
Start: 315  End: 335
Energy: -33.3 kcal/mol
Align Score: 0.002407
miRNA  3' GAU    U                         5' hsa-miR-1226-3p
             CCCU GUGUC         CCGACCACU    
             GGGA CACAG         GGCUGGUGG    
target 5'   U    U     AGGGGACGU         C 3' MAP3K14-AS1
Start: 139  End: 159
Energy: -33.3 kcal/mol
Align Score: 0.004818

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MAP3K14-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1226-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MUC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17q21.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.