Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.23

lncRNA

SVIL-AS1 ( ENSG00000224597)

miRNA

hsa-miR-1254 (MIMAT0005905)

mRNA

CCAR1 (ENSG00000060339)

Disease

SKCM

FDR

6.69E-26

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U                   GU            A 5 hsa-miR-1254
           GACG         UCCGAG    CGAAGGUCCG    
           UUGC         AGGUUC    GCUUCCAGGC    
target 5 C    AGCAACAAU      ACCU          G 3 SVIL-AS1
Start: 298  End: 318
Energy: -37 kcal/mol
Align Score: 0.000566
miRNA  3 UG  G       UC        GA 5 hsa-miR-1254
            AC UCCGAGG  GAAGGUCC     
            UG AGGCUCC  CUUCCAGG     
target 5  A  A       CC        G  3 SVIL-AS1
Start: 580  End: 600
Energy: -34.9 kcal/mol
Align Score: 0.002718
miRNA  3                      A       AGG       5 hsa-miR-1254
           UGAC           GUCCG  GGUCGA   UCCGA    
           GCUG           CGGGC  CCAGCU   GGGCU    
target 5 A    AGAGGCGCACC     GG              C 3 SVIL-AS1
Start: 8  End: 28
Energy: -32.5 kcal/mol
Align Score: 0.002005
miRNA  3                      A       AGG       5 hsa-miR-1254
           UGAC           GUCCG  GGUCGA   UCCGA    
           GCUG           CGGGC  CCAGCU   GGGCU    
target 5 A    AGAGGCGCACC     GG              C 3 SVIL-AS1
Start: 8  End: 28
Energy: -32.5 kcal/mol
Align Score: 0.004457
miRNA  3 U                   GU            A 5 hsa-miR-1254
           GACG         UCCGAG    CGAAGGUCCG    
           UUGC         AGGUUC    GCUUCCAGGC    
target 5 C    AGCAACAAU      ACCU          G 3 SVIL-AS1
Start: 145  End: 165
Energy: -37 kcal/mol
Align Score: 0.001822

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SVIL-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1254

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CCAR1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.