Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

5q13.3

lncRNA

ZBED3-AS1 ( ENSG00000250802)

miRNA

hsa-miR-149-5p (MIMAT0000450)

mRNA

GIT1 (ENSG00000108262)

Disease

SKCM

FDR

7.03E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' cccuCACUUCUGU-G-CCUCGGUCu 5' hsa-miR-149-5p
              ||||:| || | |||||||| 
target 5' acctGTGAGGCCAGCAGGAGCCAGg 3' ZBED3-AS1
Start: 558  End: 582
Energy: -28.06 kcal/mol
Align Score: 165
miRNA  3' cccuCACUUCUGU-G-CCUCGGUCu 5' hsa-miR-149-5p
              ||||:| || | |||||||| 
target 5' acctGTGAGGCCAGCAGGAGCCAGg 3' ZBED3-AS1
Start: 382  End: 406
Energy: -28.06 kcal/mol
Align Score: 165
TargetScan target site prediction
miRNA  3'    CCCUCACUUCUGUGCCUCGGUCU 5' hsa-miR-149-5p
                            ||||||| 
target 5'    UUGUCUCAUGAAUAUGAGCCAGA ZBED3-AS1
Start: 746  End: 753
Site type: 8mer-1a
Context++ Score: -0.473
miRNA  3'    CCCUCACUUCUGUGCCUCGGUCU 5' hsa-miR-149-5p
                            ||||||| 
target 5'    UUGUCUCAUGAAUAUGAGCCAGA ZBED3-AS1
Start: 500  End: 507
Site type: 8mer-1a
Context++ Score: -0.434
miRNA  3'    CCCUCACUUCUGUGCCUCGGUCU 5' hsa-miR-149-5p
                            ||||||| 
target 5'    UUGUCUCAUGAAUAUGAGCCAGA ZBED3-AS1
Start: 746  End: 753
Site type: 8mer-1a
Context++ Score: -0.473
miRNA  3'    CCCUCACUUCUGUGCCUCGGUCU 5' hsa-miR-149-5p
                            ||||||| 
target 5'    UUGUCUCAUGAAUAUGAGCCAGA ZBED3-AS1
Start: 500  End: 507
Site type: 8mer-1a
Context++ Score: -0.434
RNAbybrid target site prediction
miRNA  3' C           GUG     G     5' hsa-miR-149-5p
           CCUCAC UUCU   CCUCG UCU    
           GGAGUG AGGG   GGAGC AGA    
target 5' A      C    AA      A   A 3' ZBED3-AS1
Start: 98  End: 118
Energy: -30.7 kcal/mol
Align Score: 0.008337
miRNA  3' C           GUG     G     5' hsa-miR-149-5p
           CCUCAC UUCU   CCUCG UCU    
           GGAGUG AGGG   GGAGC AGA    
target 5' A      C    AA      A   A 3' ZBED3-AS1
Start: 67  End: 87
Energy: -30.7 kcal/mol
Align Score: 0.008372
miRNA  3' CCCU      U  G             5' hsa-miR-149-5p
              CACUUC GU   CCUCGGUCU    
              GUGAGG CA   GGAGCCAGG    
target 5'    U      C  GCA         C 3' ZBED3-AS1
Start: 561  End: 581
Energy: -31.5 kcal/mol
Align Score: 0.006731
miRNA  3'                                            5' hsa-miR-149-5p
           CCCU CACUUC UGUG               CCUCGGUCU    
           GGGA GUGGAG AUGC               GGAGCCAGG    
target 5' U    G      C    AGACGGACGGGUGCA         G 3' ZBED3-AS1
Start: 118  End: 138
Energy: -34.4 kcal/mol
Align Score: 0.008228
miRNA  3'                                            5' hsa-miR-149-5p
           CCCU CACUUC UGUG               CCUCGGUCU    
           GGGA GUGGAG AUGC               GGAGCCAGG    
target 5' U    G      C    AGACGGACGGGUGCA         G 3' ZBED3-AS1
Start: 97  End: 117
Energy: -34.4 kcal/mol
Align Score: 0.002146

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZBED3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GIT1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 5q13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.