Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

9q34.11

lncRNA

LINC00963 ( ENSG00000204054)

miRNA

hsa-miR-149-5p (MIMAT0000450)

mRNA

MTHFR (ENSG00000177000)

Disease

SKCM

FDR

1.94E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3       A                                   5 hsa-miR-149-5p
           CCCUC   CUUCUGUG              CCUCGGUCU    
           GGGAG   GAGGACAC              GGGGCCAGA    
target 5 C     GAG        CCUGGAAAGACAGU         C 3 LINC00963
Start: 960  End: 980
Energy: -40.7 kcal/mol
Align Score: 0.000905
miRNA  3      C  U                      U 5 hsa-miR-149-5p
           CCCU AC UCUGUGC       CUC GGUC    
           GGGA UG AGACACG       GAG CCAG    
target 5 U    C  C       CACCACA   C    C 3 LINC00963
Start: 205  End: 225
Energy: -29.2 kcal/mol
Align Score: 0.008231
miRNA  3 CCC    UU               U          5 hsa-miR-149-5p
             UCAC  CUG        UGCC   CGGUCU    
             GGUG  GGC        ACGG   GCCAGG    
target 5   U    GG   AGCCAGGA    UGU      G 3 LINC00963
Start: 5  End: 25
Energy: -30.7 kcal/mol
Align Score: 0.006573
miRNA  3       A                                   5 hsa-miR-149-5p
           CCCUC   CUUCUGUG              CCUCGGUCU    
           GGGAG   GAGGACAC              GGGGCCAGA    
target 5 C     GAG        CCUGGAAAGACAGU         C 3 LINC00963
Start: 44  End: 64
Energy: -40.7 kcal/mol
Align Score: 0.000289

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00963

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MTHFR

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 9q34.11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.