Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17q21.31

lncRNA

MAP3K14-AS1 ( ENSG00000267278)

miRNA

hsa-miR-197-5p (MIMAT0022691)

mRNA

IGFBP5 (ENSG00000115461)

Disease

SKCM

FDR

5.74E-4

Reported as biomarkers
0

Circulating

0

Drug resistent

0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
NA

                         
NA

TargetScan target site prediction
                                           
NA

                         
NA

RNAbybrid target site prediction
miRNA  3       G  A           AU        5 hsa-miR-197-5p
GGAGG UG CGGGAGAG GGGC
CCUUU AU GCCCUCUU CCCG
target 5 C G GGUG GAUC G 3 MAP3K14-AS1
Start: 119  End: 139
Energy: -34.1 kcal/mol
Align Score: 0.001702
miRNA  3 GGA        G     AGA         5 hsa-miR-197-5p
GGGUGACG G GAUGGGC
CCCACUGC C CUGCCCG
target 5 C AGCCA GG U 3 MAP3K14-AS1
Start: 335  End: 355
Energy: -34.2 kcal/mol
Align Score: 0.002108
miRNA  3             AC      A      C 5 hsa-miR-197-5p
GGA GGGUG GGGAG GAUGGG
CCU CCCAC CUCUC CUACCC
target 5 U GGA CAU C 3 MAP3K14-AS1
Start: 405  End: 425
Energy: -32 kcal/mol
Align Score: 0.008995
miRNA  3 GGA        G     AGA         5 hsa-miR-197-5p
GGGUGACG G GAUGGGC
CCCACUGC C CUGCCCG
target 5 C AGCCA GG U 3 MAP3K14-AS1
Start: 401  End: 421
Energy: -34.2 kcal/mol
Align Score: 0.001814
miRNA  3       G  A           AU        5 hsa-miR-197-5p
GGAGG UG CGGGAGAG GGGC
CCUUU AU GCCCUCUU CCCG
target 5 C G GGUG GAUC G 3 MAP3K14-AS1
Start: 186  End: 206
Energy: -34.1 kcal/mol
Align Score: 0.00381

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MAP3K14-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-197-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for IGFBP5

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17q21.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.