Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.31

lncRNA

LINC01089 ( ENSG00000212694)

miRNA

hsa-miR-23a-5p (MIMAT0004496)

mRNA

TLR2 (ENSG00000137462)

Disease

SKCM

FDR

9.19E-23

Reported as biomarkers
0

Circulating
0

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 UUU            G           5 hsa-miR-23a-5p
             AGGG   UAGGG UCCUUGGGG    
             UCCU   GUCCU GGGAACCUC    
target 5   C    GUC     G         G 3 LINC01089
Start: 775  End: 795
Energy: -34.4 kcal/mol
Align Score: 0.005172
miRNA  3 UUU            G           5 hsa-miR-23a-5p
             AGGG   UAGGG UCCUUGGGG    
             UCCU   GUCCU GGGAACCUC    
target 5   C    GUC     G         G 3 LINC01089
Start: 1076  End: 1096
Energy: -34.4 kcal/mol
Align Score: 0.006669
miRNA  3 UUUA                          G 5 hsa-miR-23a-5p
              GGGUAGGGG         UCCUUGGG    
              UCCGUCCCC         GGGAGCCC    
target 5    C         CCGGUCGUG        G 3 LINC01089
Start: 108  End: 128
Energy: -35.2 kcal/mol
Align Score: 0.001128
miRNA  3 UUU            G           5 hsa-miR-23a-5p
             AGGG   UAGGG UCCUUGGGG    
             UCCU   GUCCU GGGAACCUC    
target 5   C    GUC     G         G 3 LINC01089
Start: 952  End: 972
Energy: -34.4 kcal/mol
Align Score: 0.004192
miRNA  3 UUUA                    G 5 hsa-miR-23a-5p
              GGGU  AGGGGUC CUUGGG    
              CCCA  UCCUCAG GGGCCC    
target 5    G    GU       U      A 3 LINC01089
Start: 606  End: 626
Energy: -33 kcal/mol
Align Score: 0.00572

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC01089

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-23a-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TLR2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.