Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

16q12.2

lncRNA

CRNDE ( ENSG00000245694)

miRNA

hsa-miR-296-3p (MIMAT0004679)

mRNA

KCNH1 (ENSG00000143473)

Disease

SKCM

FDR

7.74E-4

Reported as biomarkers
5

Circulating
4

Drug resistent
23

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                       A       U          5 hsa-miR-296-3p
           CCUCU             CGG GGUGGGU    GGGAG    
           GGAGA             GCC CCACCCA    CCCUC    
target 5 U     GGACACUCUUGGU           UCCU     C 3 CRNDE
Start: 464  End: 484
Energy: -37.4 kcal/mol
Align Score: 0.000589
miRNA  3         GAG           AG 5 hsa-miR-296-3p
           CCUCUCG   GUGG GUUGGG     
           GGAGGGC   UGCC CAGCCU     
target 5 U       A      U      G  3 CRNDE
Start: 310  End: 330
Energy: -30.6 kcal/mol
Align Score: 0.005598
miRNA  3 C   U        G   UG      5 hsa-miR-296-3p
           CUC CGGAGG U GGU  GGAG    
           GAG GCCUCC A CCA  CUUC    
target 5 U          U G   UG    C 3 CRNDE
Start: 74  End: 94
Energy: -33 kcal/mol
Align Score: 0.005641
miRNA  3       U   A           GAG 5 hsa-miR-296-3p
           CC UC CGG G GUGGGUUGG      
           GG GG GCC C CGCCCGACC      
target 5 C  C  U   C G         A   3 CRNDE
Start: 27  End: 47
Energy: -30.3 kcal/mol
Align Score: 0.009553
miRNA  3 C      G                  AG 5 hsa-miR-296-3p
           CUCUCG AGG   UGGGU   UGGG     
           GGGAGC UCC   GCCCG   GCCC     
target 5 A      G   GCG     CGC    G  3 CRNDE
Start: 2  End: 22
Energy: -34.3 kcal/mol
Align Score: 0.001502

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CRNDE

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-296-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for KCNH1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 16q12.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.