Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

15q25.1

lncRNA

TMC3-AS1 ( ENSG00000259343)

miRNA

hsa-miR-30c-2-3p (MIMAT0004550)

mRNA

TRADD (ENSG00000102871)

Disease

SKCM

FDR

5.75E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ucucauuUGUCGGA-AGAGGGUc 5' hsa-miR-30c-2-3p
                 :|||||| ||||||| 
target 5' gtgacctGCAGCCTATCTCCCAg 3' TMC3-AS1
Start: 372  End: 394
Energy: -28.29 kcal/mol
Align Score: 162
miRNA  3' ucucauuUGUCGGA-AGAGGGUc 5' hsa-miR-30c-2-3p
                 :|||||| ||||||| 
target 5' gtgacctGCAGCCTATCTCCCAg 3' TMC3-AS1
Start: 300  End: 322
Energy: -28.29 kcal/mol
Align Score: 162
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' U                           5' hsa-miR-30c-2-3p
           CUCAUU   UGUCGGA AGAGGGUC    
           GGGUGA   GCAGCCU UCUCCCAG    
target 5' U      CCU       A        G 3' TMC3-AS1
Start: 369  End: 389
Energy: -37.7 kcal/mol
Align Score: 0.000873
miRNA  3' UC                   G                5' hsa-miR-30c-2-3p
            UCAUU             U UCGGA AGAGGGUC    
            AGUGG             A AGCCU UCUCCCAG    
target 5'  C     UGCGAUUUGCAUU G     A        G 3' TMC3-AS1
Start: 102  End: 122
Energy: -28.3 kcal/mol
Align Score: 0.007914
miRNA  3' U                           5' hsa-miR-30c-2-3p
           CUCAUU   UGUCGGA AGAGGGUC    
           GGGUGA   GCAGCCU UCUCCCAG    
target 5' U      CCU       A        G 3' TMC3-AS1
Start: 297  End: 317
Energy: -37.7 kcal/mol
Align Score: 0.000833
miRNA  3'      A         A           5' hsa-miR-30c-2-3p
           UCUC UUUGUCGGA   GAGGGUC    
           GGAG AAGCAGCCU   CUUCCAG    
target 5' G              CUC       C 3' TMC3-AS1
Start: 293  End: 313
Energy: -32.4 kcal/mol
Align Score: 0.003318
miRNA  3 U                           5 hsa-miR-30c-2-3p
           CUCAUU   UGUCGGA AGAGGGUC    
           GGGUGA   GCAGCCU UCUCCCAG    
target 5 U      CCU       A        G 3 TMC3-AS1
Start: 369  End: 389
Energy: -37.7 kcal/mol
Align Score: 0.000873

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for TMC3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-30c-2-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TRADD

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 15q25.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.