Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-345-5p (MIMAT0000772)

mRNA

NTRK3 (ENSG00000140538)

Disease

SKCM

FDR

2.71E-11

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CU    A                  A      5 hsa-miR-345-5p
            CGGG      CCUGA   UCCUC GUCG    
            GCCC      GGAUU   GGGAG CAGC    
target 5  U    CAGAUC     GGA     C    U 3 PCBP1-AS1
Start: 328  End: 348
Energy: -31.1 kcal/mol
Align Score: 0.008026
miRNA  3                          U            5 hsa-miR-345-5p
           CUCGGGAC            CUGA CCUCA GUCG    
           GAGUCCUG            GGCU GGAGU CAGU    
target 5 G        CUUUGUCACCCA          G    G 3 PCBP1-AS1
Start: 70  End: 90
Energy: -31.3 kcal/mol
Align Score: 0.007075
miRNA  3                          U            5 hsa-miR-345-5p
           CUCGGGAC            CUGA CCUCA GUCG    
           GAGUCCUG            GGCU GGAGU CAGU    
target 5 G        CUUUGUCACCCA          G    G 3 PCBP1-AS1
Start: 385  End: 405
Energy: -31.3 kcal/mol
Align Score: 0.009036
miRNA  3     G  A                  A         G 5 hsa-miR-345-5p
           CUC GG               CCUG UCCUCAGUC    
           GAG CC               GGAC GGGAGUCAG    
target 5 G   G  GAGGGGCAGCAGUGC    A         G 3 PCBP1-AS1
Start: 470  End: 490
Energy: -31.6 kcal/mol
Align Score: 0.005455
miRNA  3       GACC                            5 hsa-miR-345-5p
           CUCGG     UGAUCCUC            AGUCG    
           GAGCC     GCUAGGGG            UCAGC    
target 5 G     AGCCU        CUGAAUUCUGAC     C 3 PCBP1-AS1
Start: 17  End: 37
Energy: -29.5 kcal/mol
Align Score: 0.009651

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-345-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for NTRK3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.