Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3p14.2

lncRNA

PTPRG-AS1 ( ENSG00000241472)

miRNA

hsa-miR-665 (MIMAT0004952)

mRNA

CD274 (ENSG00000120217)

Disease

PCPG

FDR

2.03E-10

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' uccccgGAGUCGGAGGACCa 5' hsa-miR-665
                ||| ||||||||| 
target 5' tgcaagCTCCGCCTCCTGGg 3' PTPRG-AS1
Start: 397  End: 416
Energy: -24.87 kcal/mol
Align Score: 162
miRNA  3' uccccgGAGUCGGAGGACCa 5' hsa-miR-665
                ||| ||||||||| 
target 5' tgcaagCTCCGCCTCCTGGg 3' PTPRG-AS1
Start: 294  End: 313
Energy: -24.87 kcal/mol
Align Score: 162
miRNA  3' uccccgGAGUCGGAGGACCa 5' hsa-miR-665
                ||| ||||||||| 
target 5' tgcaagCTCCGCCTCCTGGg 3' PTPRG-AS1
Start: 521  End: 540
Energy: -24.87 kcal/mol
Align Score: 162
miRNA  3' uccccgGAGUCGGAGGACCa 5' hsa-miR-665
                ||| ||||||||| 
target 5' tgcaagCTCCGCCTCCTGGg 3' PTPRG-AS1
Start: 402  End: 421
Energy: -24.87 kcal/mol
Align Score: 162
miRNA  3' uccccgGAGUCGGAGGACCa 5' hsa-miR-665
                ||| ||||||||| 
target 5' tgcaagCTCCGCCTCCTGGg 3' PTPRG-AS1
Start: 457  End: 476
Energy: -24.87 kcal/mol
Align Score: 162
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' UCCC                       A 5' hsa-miR-665
              CGGAGUCGGAGG        ACC    
              GCCUCAGCCUCC        UGG    
target 5'    C            CAAAGUGC   G 3' PTPRG-AS1
Start: 689  End: 709
Energy: -33.5 kcal/mol
Align Score: 0.003386
miRNA  3' UCCC                       A 5' hsa-miR-665
              CGGAGUCGGAGG        ACC    
              GCCUUAGCCUCC        UGG    
target 5'    U            CGAGUAGC   G 3' PTPRG-AS1
Start: 437  End: 457
Energy: -31 kcal/mol
Align Score: 0.006146
miRNA  3' UCC                U         A 5' hsa-miR-665
             CCG          GAG CGGAGGACC    
             GGC          CUC GCCUCCUGG    
target 5'   C   UCACUGCAAG   C         G 3' PTPRG-AS1
Start: 449  End: 469
Energy: -30.7 kcal/mol
Align Score: 0.005997
miRNA  3 UCCC                       A 5 hsa-miR-665
              CGGAGUCGGAGG        ACC    
              GCCUCAGCCUCC        UGG    
target 5    C            CAAAGUGC   G 3 PTPRG-AS1
Start: 689  End: 709
Energy: -33.5 kcal/mol
Align Score: 0.003386
miRNA  3 UCCC                       A 5 hsa-miR-665
              CGGAGUCGGAGG        ACC    
              GCCUUAGCCUCC        UGG    
target 5    U            CGAGUAGC   G 3 PTPRG-AS1
Start: 437  End: 457
Energy: -31 kcal/mol
Align Score: 0.006146

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PTPRG-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-665

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CD274

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3p14.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.