Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

FOXO1 (ENSG00000150907)

Disease

SKCM

FDR

1.29E-3

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3        A             G  G                        5 hsa-miR-370-3p
           UGGUCC            AG UG GGUCG             UCCG    
           GCCGGG            UC GC CCGGC             AGGC    
target 5 C      GAUGCGGCGGCG  G  G     UAACGGUCCAGGG    G 3 ZEB1-AS1
Start: 92  End: 112
Energy: -31.4 kcal/mol
Align Score: 0.00356
miRNA  3 U                    UG                       G 5 hsa-miR-370-3p
           GGUCCA           AGG  GG GUCG             UCC    
           CCAGGU           UCC  CC CAGC             GGG    
target 5 C      UCAAGCGAUUC   UG  U    CUCCCGAGUAGCU   A 3 ZEB1-AS1
Start: 108  End: 128
Energy: -30.7 kcal/mol
Align Score: 0.003712
miRNA  3                          CG 5 hsa-miR-370-3p
           UGGUC  CAAGGUGG  GGUCGUC     
           GCUAG  GUUCCGCU  CCAGCAG     
target 5 G     AA        UG       C  3 ZEB1-AS1
Start: 212  End: 232
Energy: -33.1 kcal/mol
Align Score: 0.003317
miRNA  3                          CG 5 hsa-miR-370-3p
           UGGUC  CAAGGUGG  GGUCGUC     
           GCUAG  GUUCCGCU  CCAGCAG     
target 5 G     AA        UG       C  3 ZEB1-AS1
Start: 245  End: 265
Energy: -33.1 kcal/mol
Align Score: 0.002512
miRNA  3                          CG 5 hsa-miR-370-3p
           UGGUC  CAAGGUGG  GGUCGUC     
           GCUAG  GUUCCGCU  CCAGCAG     
target 5 G     AA        UG       C  3 ZEB1-AS1
Start: 456  End: 476
Energy: -33.1 kcal/mol
Align Score: 0.003123

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for FOXO1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.