Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-4674 (MIMAT0019756)

mRNA

SNCG (ENSG00000173267)

Disease

SKCM

FDR

4.28E-3

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                         C 5 hsa-miR-4674
           UCGG CGCGCAGGGCU  CGGGU    
           GGCC GUGCGUCCCGG  GCCCG    
target 5 U    A           CC     C 3 ZEB1-AS1
Start: 63  End: 83
Energy: -41.6 kcal/mol
Align Score: 0.000059
miRNA  3 U   CG   C                5 hsa-miR-4674
           CGG   CG AGGGCUCG  GGUC    
           GCC   GC UCCCGAGU  CUGG    
target 5 U   UCA  C        AG    G 3 ZEB1-AS1
Start: 129  End: 149
Energy: -30 kcal/mol
Align Score: 0.004635
miRNA  3           C    CU    UC 5 hsa-miR-4674
           UC GGCGCG AGGG  CGGG     
           GG CCGCGC UCCC  GCCC     
target 5 C  U           C     U  3 ZEB1-AS1
Start: 337  End: 357
Energy: -33.2 kcal/mol
Align Score: 0.003003
miRNA  3 UC          GC         5 hsa-miR-4674
            GGCGCGCAGG  UCGGGUC    
            CCGUGCGUCC  GGCCCAG    
target 5  U                   G 3 ZEB1-AS1
Start: 19  End: 39
Energy: -38.6 kcal/mol
Align Score: 0.000279
miRNA  3 U   C                          G   C 5 hsa-miR-4674
           CGG GCGCA               GGGCUC GGU    
           GCC CGCGU               CCCGGG CCA    
target 5 C   U     GUCCGCCCCCCGCAC      G   A 3 ZEB1-AS1
Start: 201  End: 221
Energy: -33.5 kcal/mol
Align Score: 0.002559

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-4674

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for SNCG

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.