Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-484 (MIMAT0002174)

mRNA

ZEB1 (ENSG00000148516)

Disease

SKCM

FDR

8.85E-4

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 UAG                A         ACU 5 hsa-miR-484
             CCCUC      CCCUG     CUCGG      
             GGGAG      GGGGC     GAGCC      
target 5   A     GCGGCA     GGCGG     G   3 ZEB1-AS1
Start: 131  End: 151
Energy: -31.3 kcal/mol
Align Score: 0.003747
miRNA  3    G          GA        A     5 hsa-miR-484
           UA CCCUC CCCU    CU CGG  CU    
           GU GGGAG GGGA    GA GCC  GA    
target 5 G  G     A    GGCG  U   GG  A 3 ZEB1-AS1
Start: 64  End: 84
Energy: -30.4 kcal/mol
Align Score: 0.008993
miRNA  3    G          GA        A     5 hsa-miR-484
           UA CCCUC CCCU    CU CGG  CU    
           GU GGGAG GGGA    GA GCC  GA    
target 5 G  G     A    GGCG  U   GG  A 3 ZEB1-AS1
Start: 56  End: 76
Energy: -30.4 kcal/mol
Align Score: 0.009163
miRNA  3 UA          GACU     U 5 hsa-miR-484
            GCCCUCCCCU    CGGAC    
            CGGGAGGGGG    GUCUG    
target 5  C          AUCU     U 3 ZEB1-AS1
Start: 120  End: 140
Energy: -34 kcal/mol
Align Score: 0.001776
miRNA  3    G          GA        A     5 hsa-miR-484
           UA CCCUC CCCU    CU CGG  CU    
           GU GGGAG GGGA    GA GCC  GA    
target 5 G  G     A    GGCG  U   GG  A 3 ZEB1-AS1
Start: 91  End: 111
Energy: -30.4 kcal/mol
Align Score: 0.008672

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-484

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ZEB1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.