Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

9q34.11

lncRNA

LINC00963 ( ENSG00000204054)

miRNA

hsa-miR-744-5p (MIMAT0004945)

mRNA

TLE3 (ENSG00000140332)

Disease

SKCM

FDR

1.99E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'     ACGACAAUCGGGAUCGGGGCGU 5' hsa-miR-744-5p
                            ||||||| 
target 5'    GCAGGGCCUGGAACGGCCCCGCA LINC00963
Start: 240  End: 247
Site type: 8mer-1a
Context++ Score: -0.453
RNAbybrid target site prediction
miRNA  3 A    AA       A               5 hsa-miR-744-5p
           CGAC    UCGGG     UCGGGGCGU    
           GCUG    GGCCU     GGCCCCGCA    
target 5 G    GCAG     GGAAC         U 3 LINC00963
Start: 220  End: 240
Energy: -39.5 kcal/mol
Align Score: 0.001532
miRNA  3 A     AUC         G         5 hsa-miR-744-5p
           CGACA    GGGAUCGG    GCGU    
           GCUGU    CCCUGGCU    UGCA    
target 5 C     GUUA        GGAG    G 3 LINC00963
Start: 170  End: 190
Energy: -30.6 kcal/mol
Align Score: 0.002904
miRNA  3 A    AAU   GG        GU 5 hsa-miR-744-5p
           CGAC    CG  AUCGGGGC     
           GCUG    GC  UGGCCCCG     
target 5 G    GAGU  AG        A  3 LINC00963
Start: 449  End: 469
Energy: -31.7 kcal/mol
Align Score: 0.006567
miRNA  3 A     A    GAU     C    5 hsa-miR-744-5p
           CGACA UCGG   CGGGG GU    
           GUUGU GGCU   GCCCC CA    
target 5 G     G    AU         A 3 LINC00963
Start: 76  End: 96
Energy: -29.7 kcal/mol
Align Score: 0.008527
miRNA  3        AU                  G       5 hsa-miR-744-5p
           ACGACA   CGGGA       UCGGG   CGU    
           UGCUGU   GUCUU       AGCCC   GCA    
target 5 C      GGU     GAUUUCA     AGU   G 3 LINC00963
Start: 76  End: 96
Energy: -30.3 kcal/mol
Align Score: 0.007276

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00963

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-744-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TLE3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 9q34.11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.