Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

1q25.1

lncRNA

GAS5 ( ENSG00000234741)

miRNA

hsa-miR-1254 (MIMAT0005905)

mRNA

CCAR1 (ENSG00000060339)

Disease

STAD

FDR

1.06E-5

Reported as biomarkers
18

Circulating
9

Drug resistent
39

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 UG   U      U         GA 5 hsa-miR-1254
            ACG CCGAGG CGAAGGUCC     
            UGU GGCUUC GCUUUCAGG     
target 5  A   U                G  3 GAS5
Start: 738  End: 758
Energy: -33 kcal/mol
Align Score: 0.007241
miRNA  3 UG   U     G                             5 hsa-miR-1254
            ACG  CCGA         GUCGA      AGGUCCGA    
            UGC  GGCU         CAGCU      UCCAGGCU    
target 5  A   CU    AAUUUUGUA     AUGUUG        G 3 GAS5
Start: 719  End: 739
Energy: -34.3 kcal/mol
Align Score: 0.008578
miRNA  3    A         GA       AA              A 5 hsa-miR-1254
           UG     CGUCC    GGUCG          GGUCCG    
           GC     GCGGG    CCAGC          CCAGGC    
target 5 G  GUCGG     GGAG     GCUCAGGAGC      A 3 GAS5
Start: 102  End: 122
Energy: -33.6 kcal/mol
Align Score: 0.004048
miRNA  3 UG   U      U         GA 5 hsa-miR-1254
            ACG CCGAGG CGAAGGUCC     
            UGU GGCUUC GCUUUCAGG     
target 5  A   U                G  3 GAS5
Start: 381  End: 401
Energy: -33 kcal/mol
Align Score: 0.004164
miRNA  3 UG   U     G                             5 hsa-miR-1254
            ACG  CCGA         GUCGA      AGGUCCGA    
            UGC  GGCU         CAGCU      UCCAGGCU    
target 5  A   CU    AAUUUUGUA     AUGUUG        G 3 GAS5
Start: 684  End: 704
Energy: -34.3 kcal/mol
Align Score: 0.005332

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for GAS5

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1254

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CCAR1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 1q25.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.