Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3p25.3

lncRNA

THUMPD3-AS1 ( ENSG00000206573)

miRNA

hsa-miR-1181 (MIMAT0005826)

mRNA

SOX2 (ENSG00000181449)

Disease

THCA

FDR

2.51E-8

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 G   AG              UG C 5 hsa-miR-1181
           CCG  CCCACCG   CCGC  C    
           GGU  GGGUGGC   GGUG  G    
target 5 U   GG       GAA    UG A 3 THUMPD3-AS1
Start: 42  End: 62
Energy: -35.3 kcal/mol
Align Score: 0.003194
miRNA  3 G    G           CUGCC 5 hsa-miR-1181
           CCGA CC CACCGCCG        
           GGCU GG GUGGUGGC        
target 5 U    G  U        U     3 THUMPD3-AS1
Start: 274  End: 294
Energy: -34 kcal/mol
Align Score: 0.003319
miRNA  3 G    G           CUGCC 5 hsa-miR-1181
           CCGA CC CACCGCCG        
           GGCU GG GUGGUGGC        
target 5 U    G  U        U     3 THUMPD3-AS1
Start: 265  End: 285
Energy: -34 kcal/mol
Align Score: 0.004324
miRNA  3 GCCG  C                    5 hsa-miR-1181
              AG CC ACCGCCGC   UGCC    
              UC GG UGGCGGCG   GCGG    
target 5       U  A        GCC    C 3 THUMPD3-AS1
Start: 1  End: 21
Energy: -30.6 kcal/mol
Align Score: 0.007997
miRNA  3 G    G           CUGCC 5 hsa-miR-1181
           CCGA CC CACCGCCG        
           GGCU GG GUGGUGGC        
target 5 U    G  U        U     3 THUMPD3-AS1
Start: 424  End: 444
Energy: -34 kcal/mol
Align Score: 0.002663

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for THUMPD3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1181

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for SOX2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3p25.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.