Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17p11.2

lncRNA

LRRC75A-AS1 ( ENSG00000175061)

miRNA

hsa-miR-1228-3p (MIMAT0005583)

mRNA

CSNK2A2 (ENSG00000070770)

Disease

THCA

FDR

1.68E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'  CCCCCCGCUCCG--UCCACACU 5' hsa-miR-1228-3p
               ||||      ||||||| 
target 5' GGCCUGGCGCACAUAAGGUGUGA LRRC75A-AS1
Start: 44  End: 51
Site type: 8mer-1a
Context++ Score: -0.422
miRNA  3'  CCCCCCGCUCCG--UCCACACU 5' hsa-miR-1228-3p
               ||||      ||||||| 
target 5' GGCCUGGCGCACAUAAGGUGUGA LRRC75A-AS1
Start: 43  End: 50
Site type: 8mer-1a
Context++ Score: -0.422
miRNA  3'  CCCCCCGCUCCG--UCCACACU 5' hsa-miR-1228-3p
               ||||      ||||||| 
target 5' GGCCUGGCGCACAUAAGGUGUGA LRRC75A-AS1
Start: 42  End: 49
Site type: 8mer-1a
Context++ Score: -0.423
miRNA  3'  CCCCCCGCUCCG--UCCACACU 5' hsa-miR-1228-3p
               ||||      ||||||| 
target 5' GGCCUGGCGCACAUAAGGUGUGA LRRC75A-AS1
Start: 18  End: 25
Site type: 8mer-1a
Context++ Score: -0.429
RNAbybrid target site prediction
miRNA  3                               C        5 hsa-miR-1228-3p
           CCC             CCCGC  UCCGUC AC ACU    
           GGG             GGGCG  GGGCAG UG UGA    
target 5 C   AAGCCUGUCUAGA     GA      C  U   G 3 LRRC75A-AS1
Start: 94  End: 114
Energy: -29 kcal/mol
Align Score: 0.006206
miRNA  3 C               ACACU 5 hsa-miR-1228-3p
           CCCCCGCUCCGU CC        
           GGGGGUGGGGCA GG        
target 5 U            C  C     3 LRRC75A-AS1
Start: 681  End: 701
Energy: -32.8 kcal/mol
Align Score: 0.004233
miRNA  3 C               ACACU 5 hsa-miR-1228-3p
           CCCCCGCUCCGU CC        
           GGGGGUGGGGCA GG        
target 5 U            C  C     3 LRRC75A-AS1
Start: 627  End: 647
Energy: -32.8 kcal/mol
Align Score: 0.004857
miRNA  3 C               ACACU 5 hsa-miR-1228-3p
           CCCCCGCUCCGU CC        
           GGGGGUGGGGCA GG        
target 5 U            C  C     3 LRRC75A-AS1
Start: 521  End: 541
Energy: -32.8 kcal/mol
Align Score: 0.00405

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LRRC75A-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1228-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CSNK2A2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17p11.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.