Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

1q32.3

lncRNA

PROX1-AS1 ( ENSG00000230461)

miRNA

hsa-miR-125a-3p (MIMAT0004602)

mRNA

VEGFA (ENSG00000112715)

Disease

THCA

FDR

3.86E-14

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3      G    CU      G        5 hsa-miR-125a-3p
           CCGA GGUU    UGGA UGGACA    
           GGCU CCAG    ACCU GCUUGU    
target 5 U    G    CAUU    G      G 3 PROX1-AS1
Start: 122  End: 142
Energy: -30 kcal/mol
Align Score: 0.008458
miRNA  3     A  G         UG   A 5 hsa-miR-125a-3p
           CCG GG UUCUUGGAG  GAC    
           GGC CU AAGAGCCUC  CUG    
target 5 U   A  G         UG   A 3 PROX1-AS1
Start: 288  End: 308
Energy: -34.4 kcal/mol
Align Score: 0.002441
miRNA  3     A  G         UG   A 5 hsa-miR-125a-3p
           CCG GG UUCUUGGAG  GAC    
           GGC CU AAGAGCCUC  CUG    
target 5 U   A  G         UG   A 3 PROX1-AS1
Start: 200  End: 220
Energy: -34.4 kcal/mol
Align Score: 0.002758
miRNA  3     A  G         UG   A 5 hsa-miR-125a-3p
           CCG GG UUCUUGGAG  GAC    
           GGC CU AAGAGCCUC  CUG    
target 5 U   A  G         UG   A 3 PROX1-AS1
Start: 184  End: 204
Energy: -34.4 kcal/mol
Align Score: 0.003574
miRNA  3     A  G         UG   A 5 hsa-miR-125a-3p
           CCG GG UUCUUGGAG  GAC    
           GGC CU AAGAGCCUC  CUG    
target 5 U   A  G         UG   A 3 PROX1-AS1
Start: 313  End: 333
Energy: -34.4 kcal/mol
Align Score: 0.003494

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PROX1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-125a-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for VEGFA

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 1q32.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.