Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-127-3p (MIMAT0000446)

mRNA

MAPK4 (ENSG00000141639)

Disease

THCA

FDR

3.22E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U            G     GG U 5 hsa-miR-127-3p
           CGGUUCGAGUCU  CCUA  C    
           GUCAGGUUCAGA  GGAU  G    
target 5 U            AA    UU U 3 PCBP1-AS1
Start: 138  End: 158
Energy: -30.6 kcal/mol
Align Score: 0.009665
miRNA  3            G                   5 hsa-miR-127-3p
           UC GGUUCGA U   CUGC CUAG GCU    
           AG CCAAGCU G   GGCG GAUC CGA    
target 5 U  C       G AGU    U    U   C 3 PCBP1-AS1
Start: 57  End: 77
Energy: -29.6 kcal/mol
Align Score: 0.009087
miRNA  3         G  U                   5 hsa-miR-127-3p
           UCGGUUC AG     CUGCCU  AGGCU    
           GGCCAAG UC     GAUGGA  UCUGG    
target 5 U       G  CCCAU      AG     G 3 PCBP1-AS1
Start: 218  End: 238
Energy: -31.3 kcal/mol
Align Score: 0.009882
miRNA  3            G                   5 hsa-miR-127-3p
           UC GGUUCGA U   CUGC CUAG GCU    
           AG CCAAGCU G   GGCG GAUC CGA    
target 5 U  C       G AGU    U    U   C 3 PCBP1-AS1
Start: 158  End: 178
Energy: -29.6 kcal/mol
Align Score: 0.006781
miRNA  3 U    UC   UC         CU 5 hsa-miR-127-3p
           CGGU  GAG   UGCCUAGG     
           GCCA  CUC   GCGGAUCC     
target 5 C    CU   CUC        U  3 PCBP1-AS1
Start: 32  End: 52
Energy: -30 kcal/mol
Align Score: 0.009955

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-127-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MAPK4

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.