Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

22q12.1

lncRNA

TTC28-AS1 ( ENSG00000235954)

miRNA

hsa-miR-23b-5p (MIMAT0004587)

mRNA

SMAD3 (ENSG00000166949)

Disease

THCA

FDR

3.40E-34

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 UUUAG   U               5 hsa-miR-23b-5p
               UCG ACGGUCCUUGGGU    
               AGC UGCCAGGAACUCG    
target 5     G                 U 3 TTC28-AS1
Start: 250  End: 270
Energy: -31.6 kcal/mol
Align Score: 0.005572
miRNA  3 UUUA     A             U 5 hsa-miR-23b-5p
              GUCGU CGGUCCU  UGGG    
              CGGCA GCCAGGA  GCCC    
target 5    C             AG    U 3 TTC28-AS1
Start: 574  End: 594
Energy: -32.8 kcal/mol
Align Score: 0.005061
miRNA  3 UUUA   GUA               5 hsa-miR-23b-5p
              GUC   CGGU CCUUGGGU    
              CAG   GCCG GGAACCCA    
target 5    A   AG     U        G 3 TTC28-AS1
Start: 514  End: 534
Energy: -30.6 kcal/mol
Align Score: 0.009241
miRNA  3 UUUA     A             U 5 hsa-miR-23b-5p
              GUCGU CGGUCCU  UGGG    
              CGGCA GCCAGGA  GCCC    
target 5    C             AG    U 3 TTC28-AS1
Start: 440  End: 460
Energy: -32.8 kcal/mol
Align Score: 0.003088

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for TTC28-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-23b-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for SMAD3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 22q12.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.