Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3p25.3

lncRNA

THUMPD3-AS1 ( ENSG00000206573)

miRNA

hsa-miR-29b-3p (MIMAT0000100)

mRNA

DNMT3B (ENSG00000088305)

Disease

THCA

FDR

1.73E-10

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' uuGUGACUAAAGU---UUACCACGAu 5' hsa-miR-29b-3p
            ||:|||| |:|   ||||||||| 
target 5' ctCATTGATGTTAATGAATGGTGCTa 3' THUMPD3-AS1
Start: 2823  End: 2848
Energy: -24 kcal/mol
Align Score: 172
miRNA  3' uuGUGACUAAAGU---UUACCACGAu 5' hsa-miR-29b-3p
            ||:|||| |:|   ||||||||| 
target 5' ctCATTGATGTTAATGAATGGTGCTa 3' THUMPD3-AS1
Start: 362  End: 387
Energy: -24 kcal/mol
Align Score: 172
miRNA  3' uuGUGACUAAAGU---UUACCACGAu 5' hsa-miR-29b-3p
            ||:|||| |:|   ||||||||| 
target 5' ctCATTGATGTTAATGAATGGTGCTa 3' THUMPD3-AS1
Start: 561  End: 586
Energy: -24 kcal/mol
Align Score: 172
miRNA  3' uuGUGACUAAAGU---UUACCACGAu 5' hsa-miR-29b-3p
            ||:|||| |:|   ||||||||| 
target 5' ctCATTGATGTTAATGAATGGTGCTa 3' THUMPD3-AS1
Start: 220  End: 245
Energy: -24 kcal/mol
Align Score: 172
miRNA  3' uuGUGACUAAAGU---UUACCACGAu 5' hsa-miR-29b-3p
            ||:|||| |:|   ||||||||| 
target 5' ctCATTGATGTTAATGAATGGTGCTa 3' THUMPD3-AS1
Start: 278  End: 303
Energy: -24 kcal/mol
Align Score: 172
TargetScan target site prediction
miRNA  3'    UUGUGACUAAAGUUUACCACGAU 5' hsa-miR-29b-3p
                            ||||||| 
target 5'    AUUGAUGUUAAUGAAUGGUGCUA THUMPD3-AS1
Start: 2841  End: 2848
Site type: 8mer-1a
Context++ Score: -0.429
miRNA  3'    UUGUGACUAAAGUUUACCACGAU 5' hsa-miR-29b-3p
                            ||||||| 
target 5'    AUUGAUGUUAAUGAAUGGUGCUA THUMPD3-AS1
Start: 380  End: 387
Site type: 8mer-1a
Context++ Score: -0.434
miRNA  3'    UUGUGACUAAAGUUUACCACGAU 5' hsa-miR-29b-3p
                            ||||||| 
target 5'    AUUGAUGUUAAUGAAUGGUGCUA THUMPD3-AS1
Start: 579  End: 586
Site type: 8mer-1a
Context++ Score: -0.478
miRNA  3'    UUGUGACUAAAGUUUACCACGAU 5' hsa-miR-29b-3p
                            ||||||| 
target 5'    AUUGAUGUUAAUGAAUGGUGCUA THUMPD3-AS1
Start: 238  End: 245
Site type: 8mer-1a
Context++ Score: -0.487
miRNA  3'    UUGUGACUAAAGUUUACCACGAU 5' hsa-miR-29b-3p
                            ||||||| 
target 5'    AUUGAUGUUAAUGAAUGGUGCUA THUMPD3-AS1
Start: 296  End: 303
Site type: 8mer-1a
Context++ Score: -0.491
RNAbybrid target site prediction
                                           
                       NA                  
                                           
                         
            NA

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for THUMPD3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-29b-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for DNMT3B

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3p25.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.