Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

8q24.3

lncRNA

C8orf31 ( ENSG00000177335)

miRNA

hsa-miR-331-3p (MIMAT0000760)

mRNA

ERBB2 (ENSG00000141736)

Disease

THCA

FDR

6.82E-6

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' aaGAUCCUAUCCGGGUCCCCg 5' hsa-miR-331-3p
            ||: || :|||||||||| 
target 5' agCTGTGA-GGGCCCAGGGGc 3' C8orf31
Start: 353  End: 372
Energy: -34.18 kcal/mol
Align Score: 165
miRNA  3' aagaucCUAUCCGGGUCCCCg 5' hsa-miR-331-3p
                || :|||||||||| 
target 5' gggacaGAGGGGCCCAGGGGc 3' C8orf31
Start: 430  End: 450
Energy: -32.07 kcal/mol
Align Score: 163
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' AA   C  A              5' hsa-miR-331-3p
            GAU CU UCCGGGUCCCCG    
            CUG GA GGGCCCAGGGGC    
target 5'  G   U               U 3' C8orf31
Start: 354  End: 374
Energy: -36.6 kcal/mol
Align Score: 0.003049
miRNA  3' A         U                   5' hsa-miR-331-3p
           AGAU CCUA   CCGGG    UCCCCG    
           UCUG GGGU   GGUCC    GGGGGC    
target 5' C    U    UCU     CUGG      A 3' C8orf31
Start: 518  End: 538
Energy: -33.4 kcal/mol
Align Score: 0.002739
miRNA  3' AAGA    A                         5' hsa-miR-331-3p
              UCCU            UCCGGGUCCCCG    
              AGGA            GGGCCCAGGGGC    
target 5'    C    GCUGUACGCACA            U 3' C8orf31
Start: 512  End: 532
Energy: -36.1 kcal/mol
Align Score: 0.001018
miRNA  3' AAGA    A                  5' hsa-miR-331-3p
              UCCU     UCCGGGUCCCCG    
              GGGA     GGGCCCAGGGGC    
target 5'    A    CAGAG            U 3' C8orf31
Start: 429  End: 449
Energy: -39.4 kcal/mol
Align Score: 0.000825
miRNA  3' AAGA    A                         5' hsa-miR-331-3p
              UCCU            UCCGGGUCCCCG    
              GGGA            GGGCCCAGGGGC    
target 5'    A    GCUGUACGCACA            U 3' C8orf31
Start: 436  End: 456
Energy: -36.8 kcal/mol
Align Score: 0.003538

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for C8orf31

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-331-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERBB2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 8q24.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.