Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17q21.32

lncRNA

HOXB-AS3 ( ENSG00000233101)

miRNA

hsa-miR-346 (MIMAT0000773)

mRNA

BTK (ENSG00000010671)

Disease

THCA

FDR

5.47E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
1

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U     U                  UCUGU 5 hsa-miR-346
           CUCCG CCGU       ACGCCCG        
           GGGGC GGCG       UGCGGGU        
target 5 C     C    CCUGCCC       C     3 HOXB-AS3
Start: 365  End: 385
Energy: -32.1 kcal/mol
Align Score: 0.00345
miRNA  3 UC        UAC                      5 hsa-miR-346
            UCCGUCCG   GCCCG          UCUGU    
            AGGCGGGC   UGGGC          GGGCA    
target 5  C        C       GCCUGGAGUC     U 3 HOXB-AS3
Start: 198  End: 218
Energy: -31.6 kcal/mol
Align Score: 0.005566
miRNA  3 UC        UAC                      5 hsa-miR-346
            UCCGUCCG   GCCCG          UCUGU    
            AGGCGGGC   UGGGC          GGGCA    
target 5  C        C       GCCUGGAGUC     U 3 HOXB-AS3
Start: 176  End: 196
Energy: -31.6 kcal/mol
Align Score: 0.00822
miRNA  3                                         U 5 hsa-miR-346
           UCUCCG              UCCGUA CGC CC GUCUG    
           AGAGGC              GGGCGU GCG GG CAGGC    
target 5 G      UCGGAGGAAGCCCC      G   U  U     U 3 HOXB-AS3
Start: 278  End: 298
Energy: -35.9 kcal/mol
Align Score: 0.000955
miRNA  3 U     U                  UCUGU 5 hsa-miR-346
           CUCCG CCGU       ACGCCCG        
           GGGGC GGCG       UGCGGGU        
target 5 C     C    CCUGCCC       C     3 HOXB-AS3
Start: 397  End: 417
Energy: -32.1 kcal/mol
Align Score: 0.003849

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for HOXB-AS3

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-346

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BTK

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17q21.32

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.