Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p22.1

lncRNA

SLC8A1-AS1 ( ENSG00000227028)

miRNA

hsa-miR-346 (MIMAT0000773)

mRNA

BRMS1 (ENSG00000174744)

Disease

THCA

FDR

3.20E-6

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                    CGUCUGU 5 hsa-miR-346
           UCUCCG  UCCGUACGCC          
           GGAGGC  AGGCGUGUGG          
target 5 G      UG          A       3 SLC8A1-AS1
Start: 16  End: 36
Energy: -33.2 kcal/mol
Align Score: 0.000358
miRNA  3 U             GCC          UG   5 hsa-miR-346
           CUC CGUCCGUAC         CGUC  U    
           GAG GCAGGUAUG         GCAG  G    
target 5 U   U         AAGCCUUAU    UG U 3 SLC8A1-AS1
Start: 92  End: 112
Energy: -31.1 kcal/mol
Align Score: 0.008
miRNA  3         U         U  G            5 hsa-miR-346
           UCUC CG       CCG AC CC CGUCUGU    
           GGAG GU       GGC UG GG GCAGAUA    
target 5 U    C  UCCACUU         A       A 3 SLC8A1-AS1
Start: 100  End: 120
Energy: -28 kcal/mol
Align Score: 0.00736
miRNA  3     C   U        ACG      UG   5 hsa-miR-346
           UCU  CG     CCGU   CCCGUC  U    
           AGA  GC     GGCA   GGGCAG  A    
target 5 U   AA  UGUUU    A        UG C 3 SLC8A1-AS1
Start: 138  End: 158
Energy: -28.3 kcal/mol
Align Score: 0.00551
miRNA  3         U         U  G            5 hsa-miR-346
           UCUC CG       CCG AC CC CGUCUGU    
           GGAG GU       GGC UG GG GCAGAUA    
target 5 U    C  UCCACUU         A       A 3 SLC8A1-AS1
Start: 87  End: 107
Energy: -28 kcal/mol
Align Score: 0.006783

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SLC8A1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-346

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BRMS1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p22.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.