Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q31.2

lncRNA

TTN-AS1 ( ENSG00000237298)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

HMGA2 (ENSG00000149948)

Disease

THCA

FDR

5.14E-19

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3     U               G   U     G 5 hsa-miR-370-3p
           UGG CC        AAGGU GGG CGUCC    
           GCC GG        UUCCA CCC GCAGG    
target 5 G   U  GAUCAGCU     A   U     A 3 TTN-AS1
Start: 741  End: 761
Energy: -31.8 kcal/mol
Align Score: 0.008337
miRNA  3     U               G   U     G 5 hsa-miR-370-3p
           UGG CC        AAGGU GGG CGUCC    
           GCC GG        UUCCA CCC GCAGG    
target 5 G   U  GAUCAGCU     A   U     A 3 TTN-AS1
Start: 532  End: 552
Energy: -31.8 kcal/mol
Align Score: 0.007492
miRNA  3       CA   UG                     5 hsa-miR-370-3p
           UGGUC  AGG  GGG         UCGUCCG    
           GCCAG  UCC  CCU         AGUGGGU    
target 5 A          UG   CUCAUUUUA       A 3 TTN-AS1
Start: 321  End: 341
Energy: -30.9 kcal/mol
Align Score: 0.008884
miRNA  3     U               G   U     G 5 hsa-miR-370-3p
           UGG CC        AAGGU GGG CGUCC    
           GCC GG        UUCCA CCC GCAGG    
target 5 G   U  GAUCAGCU     A   U     A 3 TTN-AS1
Start: 661  End: 681
Energy: -31.8 kcal/mol
Align Score: 0.006974
miRNA  3        A      GG              G 5 hsa-miR-370-3p
           UGGUCC AGGUGG         UCG UCC    
           ACCAGG UCCACC         AGC AGG    
target 5 C             AGCAUUACA   U   A 3 TTN-AS1
Start: 266  End: 286
Energy: -32.3 kcal/mol
Align Score: 0.006289

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for TTN-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for HMGA2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q31.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.