Basic Info

Starting a new search ...

Basic Information for the CNV-ceRNA event

Cytoband

6p22.1

lncRNA

HCG18 ( ENSG00000231074)

miRNA

hsa-miR-449c-5p (MIMAT0010251)

mRNA

MET (ENSG00000105976)

Disease

UCEC

FDR

7.29E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ugUCGGCGAUCGUUAUG-UGACGGAu 5' hsa-miR-449c-5p
            :||: ||| |: ||| ||||||| 
target 5' gtGGCTACTACCGTTACAACTGCCTg 3' HCG18
Start: 301  End: 326
Energy: -23.99 kcal/mol
Align Score: 170
miRNA  3' ugucggcGAUCGUUAUGUGACGGAu 5' hsa-miR-449c-5p
                 ||: | || |||||||| 
target 5' actgtacCTGCCCATCCACTGCCTt 3' HCG18
Start: 24  End: 48
Energy: -19.5 kcal/mol
Align Score: 162
miRNA  3' ugucggcGAUCGUUAUGUGACGGAu 5' hsa-miR-449c-5p
                 ||: | || |||||||| 
target 5' actgtacCTGCCCATCCACTGCCTt 3' HCG18
Start: 506  End: 530
Energy: -19.5 kcal/mol
Align Score: 162
miRNA  3' ugucGGCGA-UCGUUAUGUGACGGAu 5' hsa-miR-449c-5p
              |: || |  |||:|||||||| 
target 5' cgccCTTCTGAAGAATGCACTGCCTt 3' HCG18
Start: 1160  End: 1185
Energy: -24.55 kcal/mol
Align Score: 164
miRNA  3' ugucGGCGA-UCGUUAUGUGACGGAu 5' hsa-miR-449c-5p
              |: || |  |||:|||||||| 
target 5' cgccCTTCTGAAGAATGCACTGCCTt 3' HCG18
Start: 3537  End: 3562
Energy: -24.55 kcal/mol
Align Score: 164
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'       G   U  UUA   GA       5' hsa-miR-449c-5p
           UGUCG CGA CG   UGU  CGGAU    
           ACAGU GCU GC   GCG  GCCUG    
target 5' G     G      UUG   A      G 3' HCG18
Start: 44  End: 64
Energy: -29.3 kcal/mol
Align Score: 0.009366
miRNA  3'    U      U    AU         AU 5' hsa-miR-449c-5p
           UG CGGCGA CGUU    GUGACGG     
           GC GCUGCU GCAG    CACUGCU     
target 5' G  U           AAGC       G  3' HCG18
Start: 190  End: 210
Energy: -31.7 kcal/mol
Align Score: 0.00308
miRNA  3       G   U  UUA   GA       5 hsa-miR-449c-5p
           UGUCG CGA CG   UGU  CGGAU    
           ACAGU GCU GC   GCG  GCCUG    
target 5 G     G      UUG   A      G 3 HCG18
Start: 44  End: 64
Energy: -29.3 kcal/mol
Align Score: 0.009366
miRNA  3    U      U    AU         AU 5 hsa-miR-449c-5p
           UG CGGCGA CGUU    GUGACGG     
           GC GCUGCU GCAG    CACUGCU     
target 5 G  U           AAGC       G  3 HCG18
Start: 190  End: 210
Energy: -31.7 kcal/mol
Align Score: 0.00308

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for HCG18

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-449c-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MET

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 6p22.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.