Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

8q24.21

lncRNA

PVT1 ( ENSG00000249859)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

STIM1 (ENSG00000167323)

Disease

UVM

FDR

3.23E-2

Reported as biomarkers
11

Circulating
6

Drug resistent
51

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                       GGU        5 hsa-miR-185-3p
           CUGGUC UCCU       UUC   CGGGGA    
           GGCCAG AGGA       AAG   GCCCCU    
target 5 U      A    GAUUAAA   AU       C 3 PVT1
Start: 379  End: 399
Energy: -31.4 kcal/mol
Align Score: 0.008533
miRNA  3      U U              G          5 hsa-miR-185-3p
           CUGG C CCUU    UCGGUC     GGGA    
           GACC G GGAG    GGCCAG     CCCU    
target 5 U    U U    ACAC      AUCUG    C 3 PVT1
Start: 145  End: 165
Energy: -31.2 kcal/mol
Align Score: 0.004966
miRNA  3      U U              G          5 hsa-miR-185-3p
           CUGG C CCUU    UCGGUC     GGGA    
           GACC G GGAG    GGCCAG     CCCU    
target 5 U    U U    ACAC      AUCUG    C 3 PVT1
Start: 145  End: 165
Energy: -31.2 kcal/mol
Align Score: 0.00336
miRNA  3           U                    A 5 hsa-miR-185-3p
           CUGGUCUCC      UUCGGUCG    GGG    
           GGCCAGAGG      GAGCUGGU    CCC    
target 5 G         UCCCAC        CAGA   G 3 PVT1
Start: 1468  End: 1488
Energy: -33.7 kcal/mol
Align Score: 0.008557
miRNA  3      U U              G          5 hsa-miR-185-3p
           CUGG C CCUU    UCGGUC     GGGA    
           GACC G GGAG    GGCCAG     CCCU    
target 5 U    U U    ACAC      AUCUG    C 3 PVT1
Start: 142  End: 162
Energy: -31.2 kcal/mol
Align Score: 0.004037

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PVT1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for STIM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 8q24.21

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.