Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17p11.2

lncRNA

LRRC75A-AS1 ( ENSG00000175061)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

GPC1 (ENSG00000063660)

Disease

TGCT

FDR

8.20E-8

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3    U    G   CA          5 hsa-miR-149-3p
           CG GUCG GGG  GGGAGGGA    
           GC CAGC UCC  CCCUCCUU    
target 5 U       G             U 3 LRRC75A-AS1
Start: 141  End: 161
Energy: -30.6 kcal/mol
Align Score: 0.007845
miRNA  3 C  G                                  5 hsa-miR-149-3p
           GU UCGGG            GGCAGG   GAGGGA    
           CA AGCCC            CUGUCC   CUCCCU    
target 5 C  G     UGCCCUGAAUUC      UUA      C 3 LRRC75A-AS1
Start: 180  End: 200
Energy: -31.6 kcal/mol
Align Score: 0.007637
miRNA  3                     A     A 5 hsa-miR-149-3p
           CGUGUCG GGGGC  AGGG   GGG    
           GCGUGGC CCCCG  UCCU   CCC    
target 5 G       U     GC    GCG   G 3 LRRC75A-AS1
Start: 153  End: 173
Energy: -33.2 kcal/mol
Align Score: 0.002859
miRNA  3             GCA            5 hsa-miR-149-3p
           CGUG UCGGGG   GG  GAGGGA    
           GCGC AGCCCC   CC  CUCCCU    
target 5 G    C      AG   AG      G 3 LRRC75A-AS1
Start: 217  End: 237
Energy: -34.8 kcal/mol
Align Score: 0.00268
miRNA  3                     A     A 5 hsa-miR-149-3p
           CGUGUCG GGGGC  AGGG   GGG    
           GCGUGGC CCCCG  UCCU   CCC    
target 5 G       U     GC    GCG   G 3 LRRC75A-AS1
Start: 153  End: 173
Energy: -33.2 kcal/mol
Align Score: 0.002928

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LRRC75A-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GPC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17p11.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.