Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

STIM1 (ENSG00000167323)

Disease

TGCT

FDR

1.42E-2

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'    CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
                           ||||||| 
target 5'   AGAAUCUACUUGAUCCAGCCCCA ZEB1-AS1
Start: 224  End: 231
Site type: 8mer-1a
Context++ Score: -0.421
miRNA  3'    CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
                           ||||||| 
target 5'   AGAAUCUACUUGAUCCAGCCCCA ZEB1-AS1
Start: 224  End: 231
Site type: 8mer-1a
Context++ Score: -0.421
RNAbybrid target site prediction
miRNA  3' C                    G      5' hsa-miR-185-3p
           UGGUCU CCUUUC   GGUC GGGA    
           GCUAGG GGAGAG   CCAG CCCU    
target 5' C      C      AGA    G    G 3' ZEB1-AS1
Start: 157  End: 177
Energy: -32.3 kcal/mol
Align Score: 0.002526
miRNA  3'          C                        GA 5' hsa-miR-185-3p
           CUGGUCUC UUUCG             GUCGGG     
           GACCGGAG GAGGC             CAGCCC     
target 5' C        A     UACCUGACCCGCG      G  3' ZEB1-AS1
Start: 319  End: 339
Energy: -33.2 kcal/mol
Align Score: 0.002996
miRNA  3'          C                        GA 5' hsa-miR-185-3p
           CUGGUCUC UUUCG             GUCGGG     
           GACCGGAG GAGGC             CAGCCC     
target 5' C        A     UACCUGACCCGCG      G  3' ZEB1-AS1
Start: 417  End: 437
Energy: -33.2 kcal/mol
Align Score: 0.003096
miRNA  3'         CCUU               A 5' hsa-miR-185-3p
           CUGGUCU     UCGGUCG    GGG    
           GACCAGA     GGCCAGU    CCC    
target 5' G       AAAGU       GCGU   G 3' ZEB1-AS1
Start: 241  End: 261
Energy: -31.5 kcal/mol
Align Score: 0.004397
miRNA  3 C                    G      5 hsa-miR-185-3p
           UGGUCU CCUUUC   GGUC GGGA    
           GCUAGG GGAGAG   CCAG CCCU    
target 5 C      C      AGA    G    G 3 ZEB1-AS1
Start: 157  End: 177
Energy: -32.3 kcal/mol
Align Score: 0.002526

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for STIM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.