Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17q24.3

lncRNA

LINC00511 ( ENSG00000227036)

miRNA

hsa-miR-331-3p (MIMAT0000760)

mRNA

ERBB2 (ENSG00000141736)

Disease

TGCT

FDR

3.68E-9

Reported as biomarkers
0

Circulating
0

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' aaGAUCCUAUCCGGGUCCCCg 5' hsa-miR-331-3p
            || ||| | |:||||||| 
target 5' ggCTTGGA-AAGTCCAGGGGg 3' LINC00511
Start: 213  End: 232
Energy: -25.33 kcal/mol
Align Score: 161
miRNA  3' aaGAUCCUAUCCGGGUCCCCg 5' hsa-miR-331-3p
            :|| | |:||:||||||| 
target 5' ggTTATG-TGGGTCCAGGGGt 3' LINC00511
Start: 164  End: 183
Energy: -27.07 kcal/mol
Align Score: 161
miRNA  3' aaGAUCCUAUCCGGGUCCCCg 5' hsa-miR-331-3p
            :|| | |:||:||||||| 
target 5' ggTTATG-TGGGTCCAGGGGt 3' LINC00511
Start: 122  End: 141
Energy: -27.07 kcal/mol
Align Score: 161
miRNA  3' aaGAUCCUAUCCGGGUCCCCg 5' hsa-miR-331-3p
            || ||| | |:||||||| 
target 5' ggCTTGGA-AAGTCCAGGGGg 3' LINC00511
Start: 257  End: 276
Energy: -25.33 kcal/mol
Align Score: 161
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' AAGA               U        5' hsa-miR-331-3p
              UCCU    AUCCGGG CCC CG    
              GGGG    UAGGCCC GGG GC    
target 5'    C    CUCC       C   A  U 3' LINC00511
Start: 581  End: 601
Energy: -31.2 kcal/mol
Align Score: 0.008763
miRNA  3' A                                   5' hsa-miR-331-3p
           AGAUCCU             AUCCGGGUCCCCG    
           UUUGGGA             UGGGUCCAGGGGU    
target 5' C       AGCGUGGGUUAUG             C 3' LINC00511
Start: 150  End: 170
Energy: -36.8 kcal/mol
Align Score: 0.000675
miRNA  3' A                                   5' hsa-miR-331-3p
           AGAUCCU             AUCCGGGUCCCCG    
           UUUGGGA             UGGGUCCAGGGGU    
target 5' C       AGCGUGGGUUAUG             C 3' LINC00511
Start: 108  End: 128
Energy: -36.8 kcal/mol
Align Score: 0.000558
miRNA  3' A                         GU         5' hsa-miR-331-3p
           AGAUCC            UAUCCGG  CC  CCG    
           UCUGGG            GUGGGCU  GG  GGC    
target 5' C      CUUCCAGGAGGA       GU  AU   C 3' LINC00511
Start: 82  End: 102
Energy: -30.2 kcal/mol
Align Score: 0.001221
miRNA  3 AAGA               U        5 hsa-miR-331-3p
              UCCU    AUCCGGG CCC CG    
              GGGG    UAGGCCC GGG GC    
target 5    C    CUCC       C   A  U 3 LINC00511
Start: 581  End: 601
Energy: -31.2 kcal/mol
Align Score: 0.008763

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00511

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-331-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERBB2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17q24.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.