Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3q23

lncRNA

PAQR9-AS1 ( ENSG00000241570)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

CTNNB1 (ENSG00000168036)

Disease

TGCT

FDR

1.04E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U G       U              5 hsa-miR-370-3p
           G UCCAAGG GGGGU CGUCCG    
           U GGGUUCU CCCCA GCAGGU    
target 5 G G             C      C 3 PAQR9-AS1
Start: 140  End: 160
Energy: -35.7 kcal/mol
Align Score: 0.000925
miRNA  3 U             G            G 5 hsa-miR-370-3p
           GGUCCA      A GUGGGGUCGUCC    
           UCAGGU      U CAUUCUAGCAGG    
target 5 U      AGGAGG G            A 3 PAQR9-AS1
Start: 309  End: 329
Energy: -31.5 kcal/mol
Align Score: 0.005231
miRNA  3             AG  G      GU     5 hsa-miR-370-3p
           UGGU    CCA  GU GG GUC  CCG    
           ACCA    GGU  CA CC CGG  GGU    
target 5 C    CAAC   AG  G  A   GU   G 3 PAQR9-AS1
Start: 12  End: 32
Energy: -29.8 kcal/mol
Align Score: 0.006654
miRNA  3    G   AAGG       GU     5 hsa-miR-370-3p
           UG UCC    UGGGGUC  CCG    
           AU AGG    ACUUCAG  GGC    
target 5 G  G   GAAG       GU   U 3 PAQR9-AS1
Start: 196  End: 216
Energy: -28.2 kcal/mol
Align Score: 0.00856
miRNA  3 U             G            G 5 hsa-miR-370-3p
           GGUCCA      A GUGGGGUCGUCC    
           UCAGGU      U CAUUCUAGCAGG    
target 5 U      AGGAGG G            A 3 PAQR9-AS1
Start: 339  End: 359
Energy: -31.5 kcal/mol
Align Score: 0.006384

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PAQR9-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CTNNB1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3q23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.